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Approved Drugs
Inhibitors
Name:  (E)-N-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula:  C30H31ClN6O4
Similarity:  0.8306451612903226
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[4-[4-(2-pyridylmethoxy)anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide
Formula:  C27H25N5O4
Similarity:  0.8135593220338984
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide
Formula:  C28H24ClFN4O4
Similarity:  0.7868852459016393
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide
Formula:  C21H18ClFN4O3
Similarity:  0.7017543859649122
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-4-(dimethylamino)-N-[4-[4-(2-pyridylmethoxy)anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]but-2-enamide
Formula:  C30H32N6O4
Similarity:  0.6791044776119403
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[4-[4-[(3-fluorophenyl)methoxy]anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide
Formula:  C28H25FN4O4
Similarity:  0.6615384615384615
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula:  C31H31ClFN5O4
Similarity:  0.6594202898550725
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[4-[4-chloro-3-(trifluoromethyl)anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide
Formula:  C22H18ClF3N4O3
Similarity:  0.6475409836065574
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[4-(3-ethynylanilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide
Formula:  C23H20N4O3
Similarity:  0.6386554621848739
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[4-(3-cyano-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide
Formula:  C22H18FN5O3
Similarity:  0.628099173553719
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula:  C29H31ClN6O4
Similarity:  0.6159420289855072
Relative Targets:   Epidermal growth factor receptor  |
Name:  (Z)-N-[4-[3-Chloro-4-(pyridin-2-ylmethoxy)anilino]-7-ethoxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide
Formula:  C28H28ClFN6O3
Similarity:  0.6102941176470589
Relative Targets:   Epidermal growth factor receptor  | Potassium voltage-gated channel subfamily H member 2  |
Name:  (E)-N-[4-[3-Chloro-4-(pyridin-2-ylmethoxy)anilino]-7-ethoxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide
Formula:  C28H28ClFN6O3
Similarity:  0.6102941176470589
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[4-(4-bromo-2-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide
Formula:  C21H18BrFN4O3
Similarity:  0.5901639344262295
Relative Targets:   Epidermal growth factor receptor  |
Name:  Afatinib
Formula:  C24H25ClFN5O3
Similarity:  0.5891472868217055
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Dipeptidyl peptidase 1  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(isopropylamino)but-2-enamide
Formula:  C25H27ClFN5O3
Similarity:  0.5757575757575758
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-(2-methoxyethoxy)quinazolin-6-yl]prop-2-enamide
Formula:  C27H24ClFN4O4
Similarity:  0.5735294117647058
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(cyclopropylamino)but-2-enamide
Formula:  C25H25ClFN5O3
Similarity:  0.5714285714285714
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[5-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-2-(2-hydroxyethoxy)phenyl]prop-2-enamide
Formula:  C29H25ClN6O4
Similarity:  0.5664335664335665
Relative Targets:   Epidermal growth factor receptor  |