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Approved Drugs

Name:  Afatinib

Formula:  C24H25ClFN5O3

Similarity:  0.6046511627906976

Inhibitors

Name:  (E)-N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C31H31ClFN5O4

Similarity:  0.8333333333333334

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-[4-[(3-fluorophenyl)methoxy]anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide

Formula:  C28H25FN4O4

Similarity:  0.8166666666666667

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide

Formula:  C27H24ClN5O4

Similarity:  0.7868852459016393

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-(2-methoxyethoxy)quinazolin-6-yl]prop-2-enamide

Formula:  C27H24ClFN4O4

Similarity:  0.7419354838709677

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide

Formula:  C21H18ClFN4O3

Similarity:  0.7192982456140351

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-4-(dimethylamino)-N-[4-[4-[(3-fluorophenyl)methoxy]anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]but-2-enamide

Formula:  C31H32FN5O4

Similarity:  0.6838235294117647

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C30H31ClN6O4

Similarity:  0.6594202898550725

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-[4-chloro-3-(trifluoromethyl)anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide

Formula:  C22H18ClF3N4O3

Similarity:  0.6504065040650406

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-[4-(2-pyridylmethoxy)anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide

Formula:  C27H25N5O4

Similarity:  0.648854961832061

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-ethoxy-quinazolin-6-yl]-4-pyrrolidin-1-yl-but-2-enamide

Formula:  C31H31ClFN5O3

Similarity:  0.6474820143884892

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Receptor tyrosine-protein kinase erbB-4  |

Name:  N-[4-(3-cyano-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide

Formula:  C22H18FN5O3

Similarity:  0.6446280991735537

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-(3-ethynylanilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide

Formula:  C23H20N4O3

Similarity:  0.6416666666666667

Relative Targets:   Epidermal growth factor receptor  |

Name:  (Z)-N-[4-[3-Chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-methoxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide

Formula:  C28H26ClF2N5O3

Similarity:  0.6296296296296297

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-[3-Chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-methoxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide

Formula:  C28H26ClF2N5O3

Similarity:  0.6296296296296297

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-[[1-[3-(hydroxyamino)-3-oxo-propyl]triazol-4-yl]methoxy]quinazolin-6-yl]prop-2-enamide

Formula:  C30H26ClFN8O5

Similarity:  0.6258503401360545

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-ethoxy-quinazolin-6-yl]-4-(4-methylpiperazin-1-yl)but-2-enamide

Formula:  C32H34ClFN6O3

Similarity:  0.625

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Receptor tyrosine-protein kinase erbB-4  |

Name:  (E)-N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C30H31ClFN5O4

Similarity:  0.6214285714285714

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-[[1-[4-(hydroxyamino)-4-oxo-butyl]triazol-4-yl]methoxy]quinazolin-6-yl]prop-2-enamide

Formula:  C31H28ClFN8O5

Similarity:  0.6133333333333333

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-(2-ethoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C31H33ClFN5O4

Similarity:  0.6083916083916084

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |