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Approved Drugs

Name:  Dacomitinib

Formula:  C24H25ClFN5O2

Similarity:  0.5

Inhibitors

Name:  (E)-N-[4-(3-cyano-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C24H25FN6O3

Similarity:  0.7920792079207921

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-(3-ethynylanilino)-7-(2-methoxyethoxy)quinazolin-6-yl]prop-2-enamide

Formula:  C22H20N4O3

Similarity:  0.7319587628865979

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-[4-chloro-3-(trifluoromethyl)anilino]-7-(2-methoxyethoxy)quinazolin-6-yl]prop-2-enamide

Formula:  C21H18ClF3N4O3

Similarity:  0.7227722772277227

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-(3-cyano-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide

Formula:  C22H18FN5O3

Similarity:  0.6893203883495146

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-quinazolin-6-yl]prop-2-enamide

Formula:  C18H14ClFN4O2

Similarity:  0.6808510638297872

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-(3-Chloro-4-fluoroanilino)-7-prop-2-ynoxyquinazolin-6-yl]prop-2-enamide

Formula:  C20H14ClFN4O2

Similarity:  0.673469387755102

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C23H25ClFN5O3

Similarity:  0.6635514018691588

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-[2-(4-hydroxybutoxy)ethoxy]quinazolin-6-yl]prop-2-enamide

Formula:  C23H24ClFN4O4

Similarity:  0.6574074074074074

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-[[7-(2-methoxyethoxy)-6-(prop-2-enoylamino)quinazolin-4-yl]amino]-2-(trifluoromethyl)phenyl]prop-2-enamide

Formula:  C24H22F3N5O4

Similarity:  0.6517857142857143

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)pyrido[3,2-d]pyrimidin-6-yl]prop-2-enamide

Formula:  C19H17ClFN5O3

Similarity:  0.6372549019607843

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-(2-methoxyethoxy)quinazolin-6-yl]prop-2-enamide

Formula:  C27H24ClFN4O4

Similarity:  0.6324786324786325

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-[cyclopropyl(methyl)amino]but-2-enamide

Formula:  C25H27ClFN5O3

Similarity:  0.6283185840707964

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(3-methoxypropoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C24H27ClFN5O3

Similarity:  0.6160714285714286

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(1-piperidyl)but-2-enamide

Formula:  C26H29ClFN5O3

Similarity:  0.6016949152542372

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dicyclopropylamino)but-2-enamide

Formula:  C27H29ClFN5O3

Similarity:  0.5966386554621849

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(1-oxidothiomorpholin-1-ium-4-yl)but-2-enamide

Formula:  C25H27ClFN5O4S

Similarity:  0.5916666666666667

Relative Targets:   Epidermal growth factor receptor  |

Name:  Canertinib

Formula:  C24H25ClFN5O3

Similarity:  0.591304347826087

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Dipeptidyl peptidase 1  | Receptor tyrosine-protein kinase erbB-4  |

Name:  N-[4-(3-bromo-4-fluoro-anilino)-7-(3-morpholinopropoxy)quinazolin-6-yl]prop-2-enamide

Formula:  C24H25BrFN5O3

Similarity:  0.591304347826087

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(4-bromo-2-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C23H25BrFN5O3

Similarity:  0.5892857142857143

Relative Targets:   Epidermal growth factor receptor  |