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Approved Drugs
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Inhibitors
Name: N-[4-[4-chloro-3-(trifluoromethyl)anilino]-7-(2-methoxyethoxy)quinazolin-6-yl]prop-2-enamide
Formula: C21H18ClF3N4O3
Similarity: 0.7830188679245284
Relative Targets: Epidermal growth factor receptor |
Name: N-[4-[[6-(prop-2-enoylamino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-4-yl]amino]-2-(trifluoromethyl)phenyl]prop-2-enamide
Formula: C25H22F3N5O4
Similarity: 0.7288135593220338
Relative Targets: Epidermal growth factor receptor |
Name: (E)-4-(dimethylamino)-N-[4-[[6-[[(E)-4-(dimethylamino)but-2-enoyl]amino]-7-(2-methoxyethoxy)quinazolin-4-yl]amino]-2-(trifluoromethyl)phenyl]but-2-enamide
Formula: C30H36F3N7O4
Similarity: 0.6818181818181818
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-[4-chloro-3-(trifluoromethyl)anilino]-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula: C24H25ClF3N5O3
Similarity: 0.6528925619834711
Relative Targets: Epidermal growth factor receptor |
Name: N-[4-(3-cyano-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]prop-2-enamide
Formula: C21H18FN5O3
Similarity: 0.6517857142857143
Relative Targets: Epidermal growth factor receptor |
Name: N-[4-(3-ethynylanilino)-7-(2-methoxyethoxy)quinazolin-6-yl]prop-2-enamide
Formula: C22H20N4O3
Similarity: 0.6194690265486725
Relative Targets: Epidermal growth factor receptor |
Name: N-[4-[4-chloro-3-(trifluoromethyl)anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide
Formula: C22H18ClF3N4O3
Similarity: 0.5564516129032258
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula: C23H25ClFN5O3
Similarity: 0.5564516129032258
Relative Targets: Epidermal growth factor receptor |
Name: N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-(2-methoxyethoxy)quinazolin-6-yl]prop-2-enamide
Formula: C27H24ClFN4O4
Similarity: 0.5488721804511278
Relative Targets: Epidermal growth factor receptor |
Name: N-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-quinazolin-6-yl]prop-2-enamide
Formula: C18H14ClFN4O2
Similarity: 0.5446428571428571
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-cyano-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula: C24H25FN6O3
Similarity: 0.5433070866141733
Relative Targets: Epidermal growth factor receptor |
Name: N-[4-(3-chloro-4-fluoro-anilino)-7-[2-(4-hydroxybutoxy)ethoxy]quinazolin-6-yl]prop-2-enamide
Formula: C23H24ClFN4O4
Similarity: 0.5396825396825397
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(4-bromo-2-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula: C23H25BrFN5O3
Similarity: 0.5317460317460317
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-[cyclopropyl(methyl)amino]but-2-enamide
Formula: C25H27ClFN5O3
Similarity: 0.5307692307692308
Relative Targets: Epidermal growth factor receptor |
Name: N-[4-(3-Chloro-4-fluoroanilino)-7-prop-2-ynoxyquinazolin-6-yl]prop-2-enamide
Formula: C20H14ClFN4O2
Similarity: 0.5299145299145299
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(3-methoxypropoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula: C24H27ClFN5O3
Similarity: 0.5193798449612403
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)pyrido[3,2-d]pyrimidin-6-yl]prop-2-enamide
Formula: C19H17ClFN5O3
Similarity: 0.5166666666666667
Relative Targets: Epidermal growth factor receptor |
Name: (E)-4-(dimethylamino)-N-[4-(3-ethynylanilino)-7-(2-methoxyethoxy)quinazolin-6-yl]but-2-enamide
Formula: C25H27N5O3
Similarity: 0.515625
Relative Targets: Epidermal growth factor receptor |
Name: (2S)-N-[4-(3-chloro-2,4-difluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-1-prop-2-enoyl-pyrrolidine-2-carboxamide
Formula: C25H24ClF2N5O4
Similarity: 0.5111111111111111
Relative Targets: Tyrosine-protein kinase ABL1 | Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Tyrosine-protein kinase Lck | Proto-oncogene tyrosine-protein kinase receptor Ret | Insulin-like growth factor 1 receptor | Hepatocyte growth factor receptor | Platelet-derived growth factor receptor beta | Mast/stem cell growth factor receptor Kit | Fibroblast growth factor receptor 1 | Proto-oncogene tyrosine-protein kinase Src | Platelet-derived growth factor receptor alpha | Vascular endothelial growth factor receptor 1 | Fibroblast growth factor receptor 2 | Cyclin-dependent kinase 2 | Mitogen-activated protein kinase 1 | RAC-alpha serine/threonine-protein kinase | Vascular endothelial growth factor receptor 3 | Vascular endothelial growth factor receptor 2 | Receptor-type tyrosine-protein kinase FLT3 | Receptor tyrosine-protein kinase erbB-4 |