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Inhibitors

Name:  7-[3-(4-methylpiperazin-1-yl)anilino]-3-phenyl-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one

Formula:  C30H34N8O2

Similarity:  0.8709677419354839

Relative Targets:   Epidermal growth factor receptor  |

Name:  7-[4-[2-(4-methylpiperazin-1-yl)ethyl]anilino]-3-phenyl-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one

Formula:  C32H38N8O2

Similarity:  0.8307692307692308

Relative Targets:   Epidermal growth factor receptor  |

Name:  7-[3-methyl-4-(4-methylpiperazin-1-yl)anilino]-3-phenyl-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one

Formula:  C31H36N8O2

Similarity:  0.828125

Relative Targets:   Epidermal growth factor receptor  |

Name:  7-[3-chloro-4-(4-methylpiperazin-1-yl)anilino]-3-phenyl-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one

Formula:  C30H33ClN8O2

Similarity:  0.828125

Relative Targets:   Epidermal growth factor receptor  |

Name:  7-[3-fluoro-4-(4-methylpiperazin-1-yl)anilino]-3-phenyl-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one

Formula:  C30H33FN8O2

Similarity:  0.828125

Relative Targets:   Epidermal growth factor receptor  |

Name:  7-[3-methoxy-4-(4-methylpiperazin-1-yl)anilino]-3-phenyl-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one

Formula:  C31H36N8O3

Similarity:  0.8091603053435115

Relative Targets:   Epidermal growth factor receptor  |

Name:  7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-3-phenyl-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one

Formula:  C31H36N8O3

Similarity:  0.8091603053435115

Relative Targets:   Epidermal growth factor receptor  |

Name:  7-[4-(1-methyl-4-piperidyl)anilino]-3-phenyl-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one

Formula:  C31H35N7O2

Similarity:  0.7984496124031008

Relative Targets:   Epidermal growth factor receptor  |

Name:  7-[4-(4-methylpiperazin-1-yl)-3-(trifluoromethyl)anilino]-3-phenyl-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one

Formula:  C31H33F3N8O2

Similarity:  0.7851851851851852

Relative Targets:   Epidermal growth factor receptor  |

Name:  7-anilino-3-phenyl-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one

Formula:  C25H24N6O2

Similarity:  0.696

Relative Targets:   Epidermal growth factor receptor  |

Name:  3-benzyl-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-1-[(3R)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one

Formula:  C32H38N8O3

Similarity:  0.6901408450704225

Relative Targets:   Epidermal growth factor receptor  |

Name:  3-benzyl-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one

Formula:  C32H38N8O3

Similarity:  0.6901408450704225

Relative Targets:   Epidermal growth factor receptor  |

Name:  3-benzyl-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-1-[(3R)-1-prop-2-enoyl-3-piperidyl]-4H-pyrimido[4,5-d]pyrimidin-2-one

Formula:  C33H40N8O3

Similarity:  0.6530612244897959

Relative Targets:   Epidermal growth factor receptor  |

Name:  3-benzyl-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-1-[(3S)-1-prop-2-enoyl-3-piperidyl]-4H-pyrimido[4,5-d]pyrimidin-2-one

Formula:  C33H40N8O3

Similarity:  0.6530612244897959

Relative Targets:   Epidermal growth factor receptor  |

Name:  3-benzyl-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-1-(1-prop-2-enoyl-4-piperidyl)-4H-pyrimido[4,5-d]pyrimidin-2-one

Formula:  C33H40N8O3

Similarity:  0.6308724832214765

Relative Targets:   Epidermal growth factor receptor  |

Name:  7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-3-methyl-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one

Formula:  C26H34N8O3

Similarity:  0.625

Relative Targets:   Epidermal growth factor receptor  |

Name:  3-isopropyl-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one

Formula:  C28H38N8O3

Similarity:  0.6028368794326241

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[3-methyl-7-[4-(4-methylpiperazin-1-yl)anilino]-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide

Formula:  C27H30N8O2

Similarity:  0.5971223021582733

Relative Targets:   Epidermal growth factor receptor  |

Name:  3-cyclopentyl-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one

Formula:  C30H40N8O3

Similarity:  0.5704697986577181

Relative Targets:   Epidermal growth factor receptor  |