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Approved Drugs
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Inhibitors
Name: 7-[4-(4-methylpiperazin-1-yl)anilino]-3-phenyl-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C30H34N8O2
Similarity: 0.8709677419354839
Relative Targets: Epidermal growth factor receptor |
Name: 7-[3-methyl-4-(4-methylpiperazin-1-yl)anilino]-3-phenyl-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C31H36N8O2
Similarity: 0.84251968503937
Relative Targets: Epidermal growth factor receptor |
Name: 7-[3-chloro-4-(4-methylpiperazin-1-yl)anilino]-3-phenyl-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C30H33ClN8O2
Similarity: 0.84251968503937
Relative Targets: Epidermal growth factor receptor |
Name: 7-[3-fluoro-4-(4-methylpiperazin-1-yl)anilino]-3-phenyl-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C30H33FN8O2
Similarity: 0.84251968503937
Relative Targets: Epidermal growth factor receptor |
Name: 7-[3-methoxy-4-(4-methylpiperazin-1-yl)anilino]-3-phenyl-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C31H36N8O3
Similarity: 0.823076923076923
Relative Targets: Epidermal growth factor receptor |
Name: 7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-3-phenyl-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C31H36N8O3
Similarity: 0.823076923076923
Relative Targets: Epidermal growth factor receptor |
Name: 7-[4-(4-methylpiperazin-1-yl)-3-(trifluoromethyl)anilino]-3-phenyl-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C31H33F3N8O2
Similarity: 0.7985074626865671
Relative Targets: Epidermal growth factor receptor |
Name: 7-[4-[2-(4-methylpiperazin-1-yl)ethyl]anilino]-3-phenyl-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C32H38N8O2
Similarity: 0.762962962962963
Relative Targets: Epidermal growth factor receptor |
Name: 7-[4-(1-methyl-4-piperidyl)anilino]-3-phenyl-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C31H35N7O2
Similarity: 0.7313432835820896
Relative Targets: Epidermal growth factor receptor |
Name: 7-anilino-3-phenyl-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C25H24N6O2
Similarity: 0.7096774193548387
Relative Targets: Epidermal growth factor receptor |
Name: 3-benzyl-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-1-[(3R)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C32H38N8O3
Similarity: 0.7021276595744681
Relative Targets: Epidermal growth factor receptor |
Name: 3-benzyl-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C32H38N8O3
Similarity: 0.7021276595744681
Relative Targets: Epidermal growth factor receptor |
Name: 3-benzyl-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-1-[(3R)-1-prop-2-enoyl-3-piperidyl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C33H40N8O3
Similarity: 0.6643835616438356
Relative Targets: Epidermal growth factor receptor |
Name: 3-benzyl-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-1-[(3S)-1-prop-2-enoyl-3-piperidyl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C33H40N8O3
Similarity: 0.6643835616438356
Relative Targets: Epidermal growth factor receptor |
Name: 3-benzyl-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-1-(1-prop-2-enoyl-4-piperidyl)-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C33H40N8O3
Similarity: 0.6418918918918919
Relative Targets: Epidermal growth factor receptor |
Name: 7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-3-methyl-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C26H34N8O3
Similarity: 0.6370370370370371
Relative Targets: Epidermal growth factor receptor |
Name: 3-isopropyl-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C28H38N8O3
Similarity: 0.6142857142857143
Relative Targets: Epidermal growth factor receptor |
Name: N-[3-[7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-2-oxo-3-phenyl-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide
Formula: C33H34N8O3
Similarity: 0.609271523178808
Relative Targets: Epidermal growth factor receptor |
Name: 3-cyclopentyl-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C30H40N8O3
Similarity: 0.581081081081081
Relative Targets: Epidermal growth factor receptor |