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Approved Drugs
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Inhibitors
Name: 7-[3-methyl-4-(4-methylpiperazin-1-yl)anilino]-3-phenyl-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C31H36N8O2
Similarity: 0.9032258064516129
Relative Targets: Epidermal growth factor receptor |
Name: 7-[3-chloro-4-(4-methylpiperazin-1-yl)anilino]-3-phenyl-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C30H33ClN8O2
Similarity: 0.9032258064516129
Relative Targets: Epidermal growth factor receptor |
Name: 7-[3-methoxy-4-(4-methylpiperazin-1-yl)anilino]-3-phenyl-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C31H36N8O3
Similarity: 0.8818897637795275
Relative Targets: Epidermal growth factor receptor |
Name: 7-[4-(4-methylpiperazin-1-yl)-3-(trifluoromethyl)anilino]-3-phenyl-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C31H33F3N8O2
Similarity: 0.8692307692307693
Relative Targets: Epidermal growth factor receptor |
Name: 7-[3-(4-methylpiperazin-1-yl)anilino]-3-phenyl-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C30H34N8O2
Similarity: 0.84251968503937
Relative Targets: Epidermal growth factor receptor |
Name: 7-[4-(4-methylpiperazin-1-yl)anilino]-3-phenyl-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C30H34N8O2
Similarity: 0.828125
Relative Targets: Epidermal growth factor receptor |
Name: 7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-3-phenyl-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C31H36N8O3
Similarity: 0.7835820895522388
Relative Targets: Epidermal growth factor receptor |
Name: 7-[4-[2-(4-methylpiperazin-1-yl)ethyl]anilino]-3-phenyl-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C32H38N8O2
Similarity: 0.7518248175182481
Relative Targets: Epidermal growth factor receptor |
Name: 7-[4-(1-methyl-4-piperidyl)anilino]-3-phenyl-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C31H35N7O2
Similarity: 0.7205882352941176
Relative Targets: Epidermal growth factor receptor |
Name: 3-benzyl-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-1-[(3R)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C32H38N8O3
Similarity: 0.6805555555555556
Relative Targets: Epidermal growth factor receptor |
Name: 3-benzyl-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C32H38N8O3
Similarity: 0.6805555555555556
Relative Targets: Epidermal growth factor receptor |
Name: 7-anilino-3-phenyl-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C25H24N6O2
Similarity: 0.6589147286821705
Relative Targets: Epidermal growth factor receptor |
Name: 3-benzyl-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-1-[(3R)-1-prop-2-enoyl-3-piperidyl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C33H40N8O3
Similarity: 0.6442953020134228
Relative Targets: Epidermal growth factor receptor |
Name: 3-benzyl-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-1-[(3S)-1-prop-2-enoyl-3-piperidyl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C33H40N8O3
Similarity: 0.6442953020134228
Relative Targets: Epidermal growth factor receptor |
Name: 3-benzyl-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-1-(1-prop-2-enoyl-4-piperidyl)-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C33H40N8O3
Similarity: 0.6225165562913907
Relative Targets: Epidermal growth factor receptor |
Name: 7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-3-methyl-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C26H34N8O3
Similarity: 0.60431654676259
Relative Targets: Epidermal growth factor receptor |
Name: 3-isopropyl-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C28H38N8O3
Similarity: 0.5833333333333334
Relative Targets: Epidermal growth factor receptor |
Name: 3-cyclopentyl-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C30H40N8O3
Similarity: 0.5526315789473685
Relative Targets: Epidermal growth factor receptor |
Name: 1-[4-[5-chloro-2-[3-fluoro-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxy-1-piperidyl]prop-2-en-1-one
Formula: C23H28ClFN6O2
Similarity: 0.5474452554744526
Relative Targets: Epidermal growth factor receptor |