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Approved Drugs
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Inhibitors
Name: 7-[3-fluoro-4-(4-methylpiperazin-1-yl)anilino]-3-phenyl-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C30H33FN8O2
Similarity: 0.8692307692307693
Relative Targets: Epidermal growth factor receptor |
Name: 7-[3-methyl-4-(4-methylpiperazin-1-yl)anilino]-3-phenyl-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C31H36N8O2
Similarity: 0.8549618320610687
Relative Targets: Epidermal growth factor receptor |
Name: 7-[3-chloro-4-(4-methylpiperazin-1-yl)anilino]-3-phenyl-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C30H33ClN8O2
Similarity: 0.8549618320610687
Relative Targets: Epidermal growth factor receptor |
Name: 7-[3-methoxy-4-(4-methylpiperazin-1-yl)anilino]-3-phenyl-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C31H36N8O3
Similarity: 0.835820895522388
Relative Targets: Epidermal growth factor receptor |
Name: 7-[3-(4-methylpiperazin-1-yl)anilino]-3-phenyl-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C30H34N8O2
Similarity: 0.7985074626865671
Relative Targets: Epidermal growth factor receptor |
Name: 7-[4-(4-methylpiperazin-1-yl)anilino]-3-phenyl-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C30H34N8O2
Similarity: 0.7851851851851852
Relative Targets: Epidermal growth factor receptor |
Name: 7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-3-phenyl-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C31H36N8O3
Similarity: 0.7446808510638298
Relative Targets: Epidermal growth factor receptor |
Name: 7-[4-[2-(4-methylpiperazin-1-yl)ethyl]anilino]-3-phenyl-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C32H38N8O2
Similarity: 0.7152777777777778
Relative Targets: Epidermal growth factor receptor |
Name: 7-[4-(1-methyl-4-piperidyl)anilino]-3-phenyl-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C31H35N7O2
Similarity: 0.6853146853146853
Relative Targets: Epidermal growth factor receptor |
Name: 3-benzyl-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-1-[(3R)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C32H38N8O3
Similarity: 0.6490066225165563
Relative Targets: Epidermal growth factor receptor |
Name: 3-benzyl-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C32H38N8O3
Similarity: 0.6490066225165563
Relative Targets: Epidermal growth factor receptor |
Name: 7-anilino-3-phenyl-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C25H24N6O2
Similarity: 0.625
Relative Targets: Epidermal growth factor receptor |
Name: 3-benzyl-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-1-[(3R)-1-prop-2-enoyl-3-piperidyl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C33H40N8O3
Similarity: 0.6153846153846154
Relative Targets: Epidermal growth factor receptor |
Name: 3-benzyl-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-1-[(3S)-1-prop-2-enoyl-3-piperidyl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C33H40N8O3
Similarity: 0.6153846153846154
Relative Targets: Epidermal growth factor receptor |
Name: 3-benzyl-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-1-(1-prop-2-enoyl-4-piperidyl)-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C33H40N8O3
Similarity: 0.5949367088607594
Relative Targets: Epidermal growth factor receptor |
Name: 7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-3-methyl-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C26H34N8O3
Similarity: 0.5753424657534246
Relative Targets: Epidermal growth factor receptor |
Name: 3-isopropyl-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C28H38N8O3
Similarity: 0.5562913907284768
Relative Targets: Epidermal growth factor receptor |
Name: 3-cyclopentyl-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C30H40N8O3
Similarity: 0.5283018867924528
Relative Targets: Epidermal growth factor receptor |
Name: 3-cyclohexyl-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C31H42N8O3
Similarity: 0.5185185185185185
Relative Targets: Epidermal growth factor receptor |