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Approved Drugs

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Inhibitors

Name:  N-[3-(2-anilino-7-oxo-pteridin-8-yl)phenyl]prop-2-enamide

Formula:  C21H16N6O2

Similarity:  0.79

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-4-(dimethylamino)-N-[3-[2-(4-methoxyanilino)-7-oxo-pteridin-8-yl]phenyl]but-2-enamide

Formula:  C25H25N7O3

Similarity:  0.7889908256880734

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-4-(dimethylamino)-N-[4-[2-(4-methoxyanilino)-7-oxo-pteridin-8-yl]phenyl]but-2-enamide

Formula:  C25H25N7O3

Similarity:  0.6666666666666666

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-(4-chloroanilino)-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C21H15ClN6O2

Similarity:  0.6306306306306306

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-(4-methoxyanilino)-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C22H18N6O3

Similarity:  0.6283185840707964

Relative Targets:   Epidermal growth factor receptor  | Tyrosine-protein kinase BTK  |

Name:  N-[3-[2-[4-(diethylamino)anilino]-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C25H25N7O2

Similarity:  0.6271186440677966

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-(4-methoxyanilino)-7-oxo-pteridin-8-yl]phenyl]propanamide

Formula:  C22H20N6O3

Similarity:  0.6140350877192983

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  4-[[7-oxo-8-[3-(prop-2-enoylamino)phenyl]pteridin-2-yl]amino]benzamide

Formula:  C22H17N7O3

Similarity:  0.603448275862069

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-(4-acetamidoanilino)-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C23H19N7O3

Similarity:  0.6016949152542372

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[7-oxo-2-(4-pyrrolidin-1-ylanilino)pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C25H23N7O2

Similarity:  0.5645161290322581

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-[4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C26H26N8O2

Similarity:  0.5546875

Relative Targets:   Epidermal growth factor receptor  | Tyrosine-protein kinase BTK  |

Name:  N-[3-[2-(4-morpholinoanilino)-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C25H23N7O3

Similarity:  0.5511811023622047

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[7-oxo-2-[4-(1-piperidyl)anilino]pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C26H25N7O2

Similarity:  0.5511811023622047

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-(7-anilino-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl)phenyl]prop-2-enamide

Formula:  C22H20N6O2

Similarity:  0.5338983050847458

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-(4-methoxyanilino)-7-oxo-6-phenyl-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C28H22N6O3

Similarity:  0.5303030303030303

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  N-[3-[6-benzyl-2-(4-methoxyanilino)-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C29H24N6O3

Similarity:  0.5298507462686567

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  N-[4-[2-(4-chloroanilino)-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C21H15ClN6O2

Similarity:  0.5210084033613446

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-[[8-(4-methoxyphenyl)-7-oxo-pteridin-2-yl]amino]phenyl]prop-2-enamide

Formula:  C22H18N6O3

Similarity:  0.5206611570247934

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-[2-(4-methoxyanilino)-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C22H18N6O3

Similarity:  0.5206611570247934

Relative Targets:   Epidermal growth factor receptor  |