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Approved Drugs

Name:  Olmutinib

Formula:  C26H26N6O2S

Similarity:  0.5111111111111111

Inhibitors

Name:  N-[3-[7-oxo-2-(4-pyrrolidin-1-ylanilino)pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C25H23N7O2

Similarity:  0.9705882352941176

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-(4-morpholinoanilino)-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C25H23N7O3

Similarity:  0.8378378378378378

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-[4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C26H26N8O2

Similarity:  0.8230088495575221

Relative Targets:   Epidermal growth factor receptor  | Tyrosine-protein kinase BTK  |

Name:  N-[3-[2-(4-chloroanilino)-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C21H15ClN6O2

Similarity:  0.7407407407407407

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-(4-methoxyanilino)-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C22H18N6O3

Similarity:  0.7207207207207207

Relative Targets:   Epidermal growth factor receptor  | Tyrosine-protein kinase BTK  |

Name:  N-[4-[2-(4-morpholinoanilino)-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C25H23N7O3

Similarity:  0.7142857142857143

Relative Targets:   Epidermal growth factor receptor  |

Name:  4-[[7-oxo-8-[3-(prop-2-enoylamino)phenyl]pteridin-2-yl]amino]benzamide

Formula:  C22H17N7O3

Similarity:  0.7079646017699115

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-[2-[4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C26H26N8O2

Similarity:  0.7024793388429752

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-(4-acetamidoanilino)-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C23H19N7O3

Similarity:  0.6896551724137931

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-(2-anilino-7-oxo-pteridin-8-yl)phenyl]prop-2-enamide

Formula:  C21H16N6O2

Similarity:  0.6756756756756757

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-[4-(diethylamino)anilino]-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C25H25N7O2

Similarity:  0.6722689075630253

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-[2-(4-chloroanilino)-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C21H15ClN6O2

Similarity:  0.6491228070175439

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C27H28N8O3

Similarity:  0.6484375

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-[[8-(4-methoxyphenyl)-7-oxo-pteridin-2-yl]amino]phenyl]prop-2-enamide

Formula:  C22H18N6O3

Similarity:  0.6324786324786325

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-[2-(4-methoxyanilino)-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C22H18N6O3

Similarity:  0.6324786324786325

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C27H28N8O3

Similarity:  0.6230769230769231

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[7-(cyclopropylmethyl)-2-(4-morpholinoanilino)-8-oxo-purin-9-yl]phenyl]prop-2-enamide

Formula:  C28H29N7O3

Similarity:  0.6183206106870229

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  N-[3-[2-(4-methoxyanilino)-7-oxo-pteridin-8-yl]phenyl]propanamide

Formula:  C22H20N6O3

Similarity:  0.6050420168067226

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  (E)-4-(dimethylamino)-N-[3-[2-(4-methoxyanilino)-7-oxo-pteridin-8-yl]phenyl]but-2-enamide

Formula:  C25H25N7O3

Similarity:  0.5905511811023622

Relative Targets:   Epidermal growth factor receptor  |