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Approved Drugs

Name:  Olmutinib

Formula:  C26H26N6O2S

Similarity:  0.5725190839694656

Inhibitors

Name:  N-[3-[2-[4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C26H26N8O2

Similarity:  0.8571428571428571

Relative Targets:   Epidermal growth factor receptor  | Tyrosine-protein kinase BTK  |

Name:  N-[4-[2-(4-morpholinoanilino)-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C25H23N7O3

Similarity:  0.8230088495575221

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C27H28N8O3

Similarity:  0.7899159663865546

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-[2-(4-chloroanilino)-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C21H15ClN6O2

Similarity:  0.7272727272727273

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-[[8-(4-methoxyphenyl)-7-oxo-pteridin-2-yl]amino]phenyl]prop-2-enamide

Formula:  C22H18N6O3

Similarity:  0.7232142857142857

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-[2-(4-methoxyanilino)-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C22H18N6O3

Similarity:  0.7232142857142857

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[7-oxo-2-(4-pyrrolidin-1-ylanilino)pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C25H23N7O2

Similarity:  0.7203389830508474

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-(4-morpholinoanilino)-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C25H23N7O3

Similarity:  0.7024793388429752

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[7-oxo-2-[4-(1-piperidyl)anilino]pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C26H25N7O2

Similarity:  0.7024793388429752

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C27H28N8O3

Similarity:  0.6771653543307087

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C28H29N7O2

Similarity:  0.6746031746031746

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[2-[2-[4-(4-Methylpiperazin-1-yl)anilino]pyrrolo[2,3-d]pyrimidin-7-yl]phenyl]prop-2-enamide

Formula:  C26H27N7O

Similarity:  0.624

Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  | Dual specificity mitogen-activated protein kinase kinase 1  |

Name:  N-[3-[2-(4-acetamidoanilino)-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C23H19N7O3

Similarity:  0.6229508196721312

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[3-methyl-7-[4-(4-methylpiperazin-1-yl)anilino]-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide

Formula:  C27H30N8O2

Similarity:  0.6153846153846154

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-(4-chloroanilino)-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C21H15ClN6O2

Similarity:  0.6101694915254238

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-[[2-[4-(4-Methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide

Formula:  C26H27N7O2

Similarity:  0.609375

Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  |

Name:  N-[3-[2-(4-methoxyanilino)-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C22H18N6O3

Similarity:  0.6083333333333333

Relative Targets:   Epidermal growth factor receptor  | Tyrosine-protein kinase BTK  |

Name:  N-[3-[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C24H25ClN6O2

Similarity:  0.6048387096774194

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]sulfanylphenyl]prop-2-enamide

Formula:  C24H25ClN6OS

Similarity:  0.6048387096774194

Relative Targets:   Epidermal growth factor receptor  |