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Approved Drugs
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Inhibitors
Name:  N-[[2-[4-amino-6-[3-chloro-4-(2-pyridylmethoxy)anilino]pyrimidin-5-yl]oxazol-4-yl]methyl]prop-2-enamide
Formula:  C23H20ClN7O3
Similarity:  0.8380952380952381
Relative Targets:   Aurora kinase A  | Tyrosine-protein kinase JAK2  | Tyrosine-protein kinase ABL1  | Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Insulin receptor  | Insulin-like growth factor 1 receptor  | Hepatocyte growth factor receptor  | Platelet-derived growth factor receptor beta  | Mast/stem cell growth factor receptor Kit  | Fibroblast growth factor receptor 1  | Platelet-derived growth factor receptor alpha  | Vascular endothelial growth factor receptor 1  | Receptor-type tyrosine-protein kinase FLT3  | Tyrosine-protein kinase Blk  | Dual specificity mitogen-activated protein kinase kinase 1  | Focal adhesion kinase 1  | Receptor tyrosine-protein kinase erbB-4  |
Name:  N-[[2-[4-amino-6-(3-chloro-4-phenoxy-anilino)pyrimidin-5-yl]oxazol-4-yl]methyl]prop-2-enamide
Formula:  C23H19ClN6O3
Similarity:  0.8095238095238095
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  N-[[2-[4-amino-6-[3-chloro-4-(3-pyridyloxy)anilino]pyrimidin-5-yl]oxazol-4-yl]methyl]prop-2-enamide
Formula:  C22H18ClN7O3
Similarity:  0.8095238095238095
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  N-[[2-[4-amino-6-[3-chloro-4-(2-fluorophenoxy)anilino]pyrimidin-5-yl]oxazol-4-yl]methyl]prop-2-enamide
Formula:  C23H18ClFN6O3
Similarity:  0.794392523364486
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  N-[[2-[4-amino-6-[3-chloro-4-(2-methylpyrazol-3-yl)oxy-anilino]pyrimidin-5-yl]oxazol-4-yl]methyl]prop-2-enamide
Formula:  C21H19ClN8O3
Similarity:  0.7663551401869159
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  N-[[2-[4-amino-6-[3-chloro-4-(3-fluorophenoxy)anilino]pyrimidin-5-yl]oxazol-4-yl]methyl]prop-2-enamide
Formula:  C23H18ClFN6O3
Similarity:  0.7614678899082569
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  N-[[2-[4-amino-6-[3-chloro-4-[(6-methyl-3-pyridyl)oxy]anilino]pyrimidin-5-yl]oxazol-4-yl]methyl]prop-2-enamide
Formula:  C23H20ClN7O3
Similarity:  0.7614678899082569
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  N-[[2-[4-amino-6-[3-fluoro-4-(2-pyridylmethoxy)anilino]pyrimidin-5-yl]oxazol-4-yl]methyl]prop-2-enamide
Formula:  C23H20FN7O3
Similarity:  0.7545454545454545
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  N-[[2-[4-amino-6-[3-chloro-4-(4-fluorophenoxy)anilino]pyrimidin-5-yl]oxazol-4-yl]methyl]prop-2-enamide
Formula:  C23H18ClFN6O3
Similarity:  0.7454545454545455
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  N-[[2-[4-amino-6-[3-chloro-4-(2,3-dichlorophenoxy)anilino]pyrimidin-5-yl]oxazol-4-yl]methyl]prop-2-enamide
Formula:  C23H17Cl3N6O3
Similarity:  0.7321428571428571
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  N-[[2-[4-amino-6-[3-chloro-4-(2,5-dichlorophenoxy)anilino]pyrimidin-5-yl]oxazol-4-yl]methyl]prop-2-enamide
Formula:  C23H17Cl3N6O3
Similarity:  0.7168141592920354
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  N-[[2-[4-amino-6-[3-chloro-4-(2,4-dichlorophenoxy)anilino]pyrimidin-5-yl]oxazol-4-yl]methyl]prop-2-enamide
Formula:  C23H17Cl3N6O3
Similarity:  0.7168141592920354
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  N-[[2-[4-amino-6-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]pyrimidin-5-yl]oxazol-4-yl]methyl]prop-2-enamide
Formula:  C24H20ClFN6O3
Similarity:  0.7105263157894737
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  N-[[2-[4-amino-6-(3-chloro-4-fluoro-anilino)pyrimidin-5-yl]oxazol-4-yl]methyl]prop-2-enamide
Formula:  C17H14ClFN6O2
Similarity:  0.693069306930693
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  N-[[2-[4-amino-6-[3-methyl-4-[(6-methyl-3-pyridyl)oxy]anilino]pyrimidin-5-yl]oxazol-4-yl]methyl]prop-2-enamide
Formula:  C24H23N7O3
Similarity:  0.6695652173913044
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  N-[[2-[4-amino-6-[3-chloro-4-[2-methyl-5-(trifluoromethyl)pyrazol-3-yl]oxy-anilino]pyrimidin-5-yl]oxazol-4-yl]methyl]prop-2-enamide
Formula:  C22H18ClF3N8O3
Similarity:  0.6638655462184874
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  N-[[2-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]pyrimidin-5-yl]oxazol-4-yl]methyl]prop-2-enamide
Formula:  C23H19ClN6O3
Similarity:  0.6608695652173913
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  N-[[2-[4-amino-6-(3,4-dichloro-2-fluoro-anilino)pyrimidin-5-yl]oxazol-4-yl]methyl]prop-2-enamide
Formula:  C17H13Cl2FN6O2
Similarity:  0.5871559633027523
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  N-[[5-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]pyrimidin-5-yl]isoxazol-3-yl]methyl]prop-2-enamide
Formula:  C23H19ClN6O3
Similarity:  0.5528455284552846
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |