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Approved Drugs
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Inhibitors
Name:  N-[[2-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]pyrimidin-5-yl]oxazol-4-yl]methyl]prop-2-enamide
Formula:  C23H19ClN6O3
Similarity:  0.8113207547169812
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  N-[3-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]pyrimidin-5-yl]phenyl]prop-2-enamide
Formula:  C25H20ClN5O2
Similarity:  0.6842105263157895
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  N-[3-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]pyrimidin-5-yl]prop-2-ynyl]prop-2-enamide
Formula:  C22H18ClN5O2
Similarity:  0.6788990825688074
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  N-[[2-[4-amino-6-[3-chloro-4-(2-pyridylmethoxy)anilino]pyrimidin-5-yl]oxazol-4-yl]methyl]prop-2-enamide
Formula:  C23H20ClN7O3
Similarity:  0.6724137931034483
Relative Targets:   Aurora kinase A  | Tyrosine-protein kinase JAK2  | Tyrosine-protein kinase ABL1  | Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Insulin receptor  | Insulin-like growth factor 1 receptor  | Hepatocyte growth factor receptor  | Platelet-derived growth factor receptor beta  | Mast/stem cell growth factor receptor Kit  | Fibroblast growth factor receptor 1  | Platelet-derived growth factor receptor alpha  | Vascular endothelial growth factor receptor 1  | Receptor-type tyrosine-protein kinase FLT3  | Tyrosine-protein kinase Blk  | Dual specificity mitogen-activated protein kinase kinase 1  | Focal adhesion kinase 1  | Receptor tyrosine-protein kinase erbB-4  |
Name:  N-[[2-[4-amino-6-[3-fluoro-4-(2-pyridylmethoxy)anilino]pyrimidin-5-yl]oxazol-4-yl]methyl]prop-2-enamide
Formula:  C23H20FN7O3
Similarity:  0.5901639344262295
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  4-amino-6-[3-chloro-4-(2-pyridylmethoxy)anilino]-N-[2-(prop-2-enoylamino)ethyl]pyrimidine-5-carboxamide
Formula:  C22H22ClN7O3
Similarity:  0.5833333333333334
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  N-[3-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide
Formula:  C27H21ClN6O2
Similarity:  0.5581395348837209
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[[2-[4-amino-6-[3-chloro-4-(2-pyridyloxy)anilino]pyrimidin-5-yl]oxazol-4-yl]methyl]prop-2-enamide
Formula:  C22H18ClN7O3
Similarity:  0.5528455284552846
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  N-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide
Formula:  C27H24ClN5O4
Similarity:  0.5454545454545454
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[[2-[4-amino-6-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]pyrimidin-5-yl]oxazol-4-yl]methyl]prop-2-enamide
Formula:  C24H20ClFN6O3
Similarity:  0.53125
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  N-[[2-[4-amino-6-[3-chloro-4-(3-pyridyloxy)anilino]pyrimidin-5-yl]oxazol-4-yl]methyl]prop-2-enamide
Formula:  C22H18ClN7O3
Similarity:  0.528
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  N-[5-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-2-(2-hydroxyethoxy)phenyl]prop-2-enamide
Formula:  C29H25ClN6O4
Similarity:  0.5251798561151079
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[[2-[4-amino-6-(3-chloro-4-phenoxy-anilino)pyrimidin-5-yl]oxazol-4-yl]methyl]prop-2-enamide
Formula:  C23H19ClN6O3
Similarity:  0.5158730158730159
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  N-[5-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-2-(3-hydroxypropoxy)phenyl]prop-2-enamide
Formula:  C30H27ClN6O4
Similarity:  0.5140845070422535
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[5-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-2-[2-(dimethylamino)ethoxy]phenyl]prop-2-enamide
Formula:  C31H30ClN7O3
Similarity:  0.5069444444444444
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[5-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-2-(2-methoxy-1-methyl-ethoxy)phenyl]prop-2-enamide
Formula:  C31H29ClN6O4
Similarity:  0.5069444444444444
Relative Targets:   Epidermal growth factor receptor  |