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Approved Drugs
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Inhibitors
Name:  N-[3-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide
Formula:  C27H21ClN6O2
Similarity:  0.7946428571428571
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[[5-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]pyrimidin-5-yl]isoxazol-3-yl]methyl]prop-2-enamide
Formula:  C23H19ClN6O3
Similarity:  0.6842105263157895
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  N-[[2-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]pyrimidin-5-yl]oxazol-4-yl]methyl]prop-2-enamide
Formula:  C23H19ClN6O3
Similarity:  0.6695652173913044
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  N-[3-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]pyrimidin-5-yl]prop-2-ynyl]prop-2-enamide
Formula:  C22H18ClN5O2
Similarity:  0.6339285714285714
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  N-[3-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide
Formula:  C28H21ClFN5O2
Similarity:  0.624
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[5-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-2-(2-hydroxyethoxy)phenyl]prop-2-enamide
Formula:  C29H25ClN6O4
Similarity:  0.6060606060606061
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[5-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-2-(3-hydroxypropoxy)phenyl]prop-2-enamide
Formula:  C30H27ClN6O4
Similarity:  0.5925925925925926
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[5-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-2-[2-(dimethylamino)ethoxy]phenyl]prop-2-enamide
Formula:  C31H30ClN7O3
Similarity:  0.583941605839416
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[5-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-2-(2-methoxy-1-methyl-ethoxy)phenyl]prop-2-enamide
Formula:  C31H29ClN6O4
Similarity:  0.583941605839416
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide
Formula:  C38H35ClN8O2
Similarity:  0.5723684210526315
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide
Formula:  C27H24ClN5O4
Similarity:  0.5572519083969466
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[[2-[4-amino-6-[3-chloro-4-(2-pyridylmethoxy)anilino]pyrimidin-5-yl]oxazol-4-yl]methyl]prop-2-enamide
Formula:  C23H20ClN7O3
Similarity:  0.552
Relative Targets:   Aurora kinase A  | Tyrosine-protein kinase JAK2  | Tyrosine-protein kinase ABL1  | Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Insulin receptor  | Insulin-like growth factor 1 receptor  | Hepatocyte growth factor receptor  | Platelet-derived growth factor receptor beta  | Mast/stem cell growth factor receptor Kit  | Fibroblast growth factor receptor 1  | Platelet-derived growth factor receptor alpha  | Vascular endothelial growth factor receptor 1  | Receptor-type tyrosine-protein kinase FLT3  | Tyrosine-protein kinase Blk  | Dual specificity mitogen-activated protein kinase kinase 1  | Focal adhesion kinase 1  | Receptor tyrosine-protein kinase erbB-4  |
Name:  4-amino-6-[3-chloro-4-(2-pyridylmethoxy)anilino]-N-[2-(prop-2-enoylamino)ethyl]pyrimidine-5-carboxamide
Formula:  C22H22ClN7O3
Similarity:  0.5447154471544715
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  N-[3-[4-[(1-benzylindazol-5-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide
Formula:  C29H23N7O
Similarity:  0.5185185185185185
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[4-(4-benzylanilino)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide
Formula:  C28H23N5O
Similarity:  0.5076923076923077
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[4-(4-phenoxyanilino)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide
Formula:  C27H21N5O2
Similarity:  0.5076923076923077
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[4-[(2-benzyl-1H-benzimidazol-5-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide
Formula:  C29H23N7O
Similarity:  0.5073529411764706
Relative Targets:   Epidermal growth factor receptor  |