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Inhibitors

Name:  N-[3-[7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-2-oxo-3-phenyl-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide

Formula:  C33H34N8O3

Similarity:  0.8623188405797102

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[3-(4-benzyloxyphenyl)-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide

Formula:  C40H40N8O4

Similarity:  0.7784810126582279

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide

Formula:  C28H32N8O3

Similarity:  0.7720588235294118

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-3-(2-naphthyl)-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide

Formula:  C37H36N8O3

Similarity:  0.7697368421052632

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-2-oxo-3-(4-phenylphenyl)-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide

Formula:  C39H38N8O3

Similarity:  0.7628205128205128

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-2-oxo-3-(4-phenoxyphenyl)-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide

Formula:  C39H38N8O4

Similarity:  0.7484276729559748

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[3-isopropyl-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide

Formula:  C30H36N8O3

Similarity:  0.7446808510638298

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[3-cyclopropyl-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide

Formula:  C30H34N8O3

Similarity:  0.7394366197183099

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[2-[3-benzyl-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]ethyl]prop-2-enamide

Formula:  C30H36N8O3

Similarity:  0.7342657342657343

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[7-[2-methoxy-4-(4-methyl-1,4-diazepan-1-yl)anilino]-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide

Formula:  C29H34N8O3

Similarity:  0.7304964539007093

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[7-[2-ethoxy-4-(4-methylpiperazin-1-yl)anilino]-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide

Formula:  C29H34N8O3

Similarity:  0.7183098591549296

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[7-[2-isopropoxy-4-(4-methylpiperazin-1-yl)anilino]-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide

Formula:  C30H36N8O3

Similarity:  0.696551724137931

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[3-methyl-7-[2-methyl-4-(4-methylpiperazin-1-yl)anilino]-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide

Formula:  C28H32N8O2

Similarity:  0.6879432624113475

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[7-[2-fluoro-4-(4-methylpiperazin-1-yl)anilino]-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide

Formula:  C27H29FN8O2

Similarity:  0.6879432624113475

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-[3-benzyl-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]cyclohexyl]prop-2-enamide

Formula:  C34H42N8O3

Similarity:  0.6774193548387096

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-[2-Methoxy-4-(4-methylpiperazin-1-yl)anilino]-7-oxopyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide

Formula:  C28H29N7O3

Similarity:  0.6713286713286714

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[7-[2-methoxy-4-(1-piperidyl)anilino]-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide

Formula:  C28H31N7O3

Similarity:  0.6713286713286714

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[7-(2-methoxy-4-morpholino-anilino)-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide

Formula:  C27H29N7O4

Similarity:  0.6713286713286714

Relative Targets:   Epidermal growth factor receptor  |

Name:  3-benzyl-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-1-[(3R)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one

Formula:  C32H38N8O3

Similarity:  0.6710526315789473

Relative Targets:   Epidermal growth factor receptor  |