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Inhibitors

Name:  N-[3-[3-methyl-7-[2-methyl-4-(4-methylpiperazin-1-yl)anilino]-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide

Formula:  C28H32N8O2

Similarity:  0.8947368421052632

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide

Formula:  C28H32N8O3

Similarity:  0.8717948717948718

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[7-[2-ethoxy-4-(4-methylpiperazin-1-yl)anilino]-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide

Formula:  C29H34N8O3

Similarity:  0.85

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[7-[2-isopropoxy-4-(4-methylpiperazin-1-yl)anilino]-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide

Formula:  C30H36N8O3

Similarity:  0.8360655737704918

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[7-[2-methoxy-4-(4-methyl-1,4-diazepan-1-yl)anilino]-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide

Formula:  C29H34N8O3

Similarity:  0.819672131147541

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[3-methyl-7-[4-(4-methylpiperazin-1-yl)anilino]-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide

Formula:  C27H30N8O2

Similarity:  0.8135593220338984

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[7-[3-methoxy-4-(4-methylpiperazin-1-yl)anilino]-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide

Formula:  C28H32N8O3

Similarity:  0.7661290322580645

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[3-isopropyl-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide

Formula:  C30H36N8O3

Similarity:  0.7637795275590551

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[3-cyclopropyl-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide

Formula:  C30H34N8O3

Similarity:  0.7578125

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[7-[2-methoxy-4-(1-piperidyl)anilino]-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide

Formula:  C28H31N7O3

Similarity:  0.736

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[7-(2-methoxy-4-morpholino-anilino)-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide

Formula:  C27H29N7O4

Similarity:  0.736

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-2-oxo-3-phenyl-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide

Formula:  C33H34N8O3

Similarity:  0.7028985507246377

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[7-[4-[4-(dimethylamino)-1-piperidyl]-2-methoxy-anilino]-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide

Formula:  C30H36N8O3

Similarity:  0.696969696969697

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[3-benzyl-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide

Formula:  C34H36N8O3

Similarity:  0.6879432624113475

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-3-(2-naphthyl)-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide

Formula:  C37H36N8O3

Similarity:  0.6466666666666666

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-6,7-dioxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C28H30N8O4

Similarity:  0.6370370370370371

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[7-[4-(dimethylamino)-2-methoxy-anilino]-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide

Formula:  C25H27N7O3

Similarity:  0.6349206349206349

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-[2-Methoxy-4-(4-methylpiperazin-1-yl)anilino]-7-oxopyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide

Formula:  C28H29N7O3

Similarity:  0.631578947368421

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C27H28N8O3

Similarity:  0.631578947368421

Relative Targets:   Epidermal growth factor receptor  |