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Approved Drugs
Name: Olmutinib
Formula: C26H26N6O2S
Similarity: 0.5877862595419847
Inhibitors
Name: N-[3-[3-methyl-7-[2-methyl-4-(4-methylpiperazin-1-yl)anilino]-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide
Formula: C28H32N8O2
Similarity: 0.8135593220338984
Relative Targets: Epidermal growth factor receptor |
Name: N-[3-[7-[2-fluoro-4-(4-methylpiperazin-1-yl)anilino]-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide
Formula: C27H29FN8O2
Similarity: 0.8135593220338984
Relative Targets: Epidermal growth factor receptor |
Name: N-[3-[7-[3-methoxy-4-(4-methylpiperazin-1-yl)anilino]-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide
Formula: C28H32N8O3
Similarity: 0.7933884297520661
Relative Targets: Epidermal growth factor receptor |
Name: N-[3-[7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide
Formula: C28H32N8O3
Similarity: 0.7933884297520661
Relative Targets: Epidermal growth factor receptor |
Name: N-[3-[7-[2-ethoxy-4-(4-methylpiperazin-1-yl)anilino]-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide
Formula: C29H34N8O3
Similarity: 0.7741935483870968
Relative Targets: Epidermal growth factor receptor |
Name: N-[3-[7-[2-isopropoxy-4-(4-methylpiperazin-1-yl)anilino]-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide
Formula: C30H36N8O3
Similarity: 0.7619047619047619
Relative Targets: Epidermal growth factor receptor |
Name: N-[3-[7-[2-methoxy-4-(4-methyl-1,4-diazepan-1-yl)anilino]-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide
Formula: C29H34N8O3
Similarity: 0.746031746031746
Relative Targets: Epidermal growth factor receptor |
Name: N-[3-[2-[4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide
Formula: C26H26N8O2
Similarity: 0.7073170731707317
Relative Targets: Epidermal growth factor receptor | Tyrosine-protein kinase BTK |
Name: N-[3-[3-isopropyl-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide
Formula: C30H36N8O3
Similarity: 0.6946564885496184
Relative Targets: Epidermal growth factor receptor |
Name: N-[3-[3-cyclopropyl-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide
Formula: C30H34N8O3
Similarity: 0.6893939393939394
Relative Targets: Epidermal growth factor receptor |
Name: N-[3-[7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-2-oxo-3-phenyl-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide
Formula: C33H34N8O3
Similarity: 0.6762589928057554
Relative Targets: Epidermal growth factor receptor |
Name: N-[3-(7-anilino-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl)phenyl]prop-2-enamide
Formula: C22H20N6O2
Similarity: 0.6695652173913044
Relative Targets: Epidermal growth factor receptor |
Name: N-[3-[7-[2-methoxy-4-(1-piperidyl)anilino]-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide
Formula: C28H31N7O3
Similarity: 0.6666666666666666
Relative Targets: Epidermal growth factor receptor |
Name: N-[3-[7-(2-methoxy-4-morpholino-anilino)-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide
Formula: C27H29N7O4
Similarity: 0.6666666666666666
Relative Targets: Epidermal growth factor receptor |
Name: N-[3-[3-benzyl-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide
Formula: C34H36N8O3
Similarity: 0.6619718309859155
Relative Targets: Epidermal growth factor receptor |
Name: N-[3-[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula: C24H25ClN6O2
Similarity: 0.6611570247933884
Relative Targets: Epidermal growth factor receptor |
Name: N-[3-[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]sulfanylphenyl]prop-2-enamide
Formula: C24H25ClN6OS
Similarity: 0.6611570247933884
Relative Targets: Epidermal growth factor receptor |
Name: N-[3-[5-bromo-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula: C24H25BrN6O2
Similarity: 0.6611570247933884
Relative Targets: Epidermal growth factor receptor |
Name: N-[3-[[2-[4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide
Formula: C28H29N7O2
Similarity: 0.6511627906976745
Relative Targets: Tyrosine-protein kinase JAK3 |