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Approved Drugs
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Inhibitors
Name:  N-[3-(7-anilino-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl)phenyl]prop-2-enamide
Formula:  C22H20N6O2
Similarity:  0.7142857142857143
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[7-[4-(dimethylamino)-2-methoxy-anilino]-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide
Formula:  C25H27N7O3
Similarity:  0.6470588235294118
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[3-methyl-7-[4-(4-methylpiperazin-1-yl)anilino]-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide
Formula:  C27H30N8O2
Similarity:  0.6
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[3-methyl-7-[2-methyl-4-(4-methylpiperazin-1-yl)anilino]-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide
Formula:  C28H32N8O2
Similarity:  0.5892857142857143
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[7-[2-fluoro-4-(4-methylpiperazin-1-yl)anilino]-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide
Formula:  C27H29FN8O2
Similarity:  0.5892857142857143
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[7-[2-methoxy-4-(1-piperidyl)anilino]-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide
Formula:  C28H31N7O3
Similarity:  0.584070796460177
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[7-(2-methoxy-4-morpholino-anilino)-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide
Formula:  C27H29N7O4
Similarity:  0.584070796460177
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[7-[3-methoxy-4-(4-methylpiperazin-1-yl)anilino]-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide
Formula:  C28H32N8O3
Similarity:  0.5739130434782609
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide
Formula:  C28H32N8O3
Similarity:  0.5739130434782609
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[7-[2-ethoxy-4-(4-methylpiperazin-1-yl)anilino]-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide
Formula:  C29H34N8O3
Similarity:  0.559322033898305
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[7-[2-methoxy-4-(4-methyl-1,4-diazepan-1-yl)anilino]-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide
Formula:  C29H34N8O3
Similarity:  0.559322033898305
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[7-[4-[4-(dimethylamino)-1-piperidyl]-2-methoxy-anilino]-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide
Formula:  C30H36N8O3
Similarity:  0.55
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[7-[2-isopropoxy-4-(4-methylpiperazin-1-yl)anilino]-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide
Formula:  C30H36N8O3
Similarity:  0.55
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[3-isopropyl-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide
Formula:  C30H36N8O3
Similarity:  0.5
Relative Targets:   Epidermal growth factor receptor  |