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Inhibitors

Name:  N-[3-[3-methyl-7-(methylamino)-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide

Formula:  C17H18N6O2

Similarity:  0.7142857142857143

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[3-methyl-7-[4-(4-methylpiperazin-1-yl)anilino]-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide

Formula:  C27H30N8O2

Similarity:  0.6695652173913044

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[7-[4-(dimethylamino)-2-methoxy-anilino]-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide

Formula:  C25H27N7O3

Similarity:  0.6576576576576577

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-(2-anilino-7-oxo-pteridin-8-yl)phenyl]prop-2-enamide

Formula:  C21H16N6O2

Similarity:  0.6504854368932039

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[7-[3-methoxy-4-(4-methylpiperazin-1-yl)anilino]-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide

Formula:  C28H32N8O3

Similarity:  0.6147540983606558

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[3-methyl-7-[2-methyl-4-(4-methylpiperazin-1-yl)anilino]-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide

Formula:  C28H32N8O2

Similarity:  0.6033057851239669

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[7-[2-fluoro-4-(4-methylpiperazin-1-yl)anilino]-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide

Formula:  C27H29FN8O2

Similarity:  0.6033057851239669

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[7-[2-methoxy-4-(1-piperidyl)anilino]-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide

Formula:  C28H31N7O3

Similarity:  0.5983606557377049

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[7-(2-methoxy-4-morpholino-anilino)-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide

Formula:  C27H29N7O4

Similarity:  0.5983606557377049

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide

Formula:  C28H32N8O3

Similarity:  0.5887096774193549

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[7-[2-ethoxy-4-(4-methylpiperazin-1-yl)anilino]-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide

Formula:  C29H34N8O3

Similarity:  0.5748031496062992

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[7-[2-methoxy-4-(4-methyl-1,4-diazepan-1-yl)anilino]-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide

Formula:  C29H34N8O3

Similarity:  0.5748031496062992

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-2-oxo-3-phenyl-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide

Formula:  C33H34N8O3

Similarity:  0.5661764705882353

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[7-[4-[4-(dimethylamino)-1-piperidyl]-2-methoxy-anilino]-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide

Formula:  C30H36N8O3

Similarity:  0.5658914728682171

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[7-[2-isopropoxy-4-(4-methylpiperazin-1-yl)anilino]-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide

Formula:  C30H36N8O3

Similarity:  0.5658914728682171

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[3-benzyl-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide

Formula:  C34H36N8O3

Similarity:  0.5539568345323741

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[3-(2-anilino-7-oxo-pteridin-8-yl)phenyl]-4-(dimethylamino)but-2-enamide

Formula:  C24H23N7O2

Similarity:  0.5338983050847458

Relative Targets:   Epidermal growth factor receptor  |

Name:  7-anilino-3-phenyl-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one

Formula:  C25H24N6O2

Similarity:  0.5294117647058824

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-(4-chloroanilino)-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C21H15ClN6O2

Similarity:  0.5221238938053098

Relative Targets:   Epidermal growth factor receptor  |