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Approved Drugs
Inhibitors
Name:  N-[3-[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C24H25ClN6O2
Similarity:  0.7904761904761904
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[5-bromo-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C24H25BrN6O2
Similarity:  0.7904761904761904
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[2-[2-[4-(4-Methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C24H26N6O2
Similarity:  0.7884615384615384
Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  | Dual specificity mitogen-activated protein kinase kinase 1  |
Name:  Olmutinib
Formula:  C26H26N6O2S
Similarity:  0.7410714285714286
Relative Targets:   Tyrosine-protein kinase BTK  |
Name:  N-[3-[[2-[4-(4-Methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide
Formula:  C26H27N7O2
Similarity:  0.7410714285714286
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[2-[4-(4-methylpiperazin-1-yl)anilino]-5-(trifluoromethyl)pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C25H25F3N6O2
Similarity:  0.7410714285714286
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[[3-chloro-6-[4-(4-methylpiperazin-1-yl)anilino]-2-pyridyl]oxy]phenyl]prop-2-enamide
Formula:  C25H26ClN5O2
Similarity:  0.7407407407407407
Relative Targets:   Dipeptidyl peptidase 1  |
Name:  N-[3-[[2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide
Formula:  C25H28N8O2
Similarity:  0.7321428571428571
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[[2-[4-(4-methylpiperazin-1-yl)anilino]-9H-purin-6-yl]oxy]phenyl]prop-2-enamide
Formula:  C25H26N8O2
Similarity:  0.7256637168141593
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]sulfanylphenyl]prop-2-enamide
Formula:  C24H25ClN6OS
Similarity:  0.6936936936936937
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[[6-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-2-pyridyl]oxy]phenyl]prop-2-enamide
Formula:  C26H29N5O3
Similarity:  0.6608695652173913
Relative Targets:   Dipeptidyl peptidase 1  |
Name:  N-[3-[2-[4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide
Formula:  C26H26N8O2
Similarity:  0.6554621848739496
Relative Targets:   Epidermal growth factor receptor  | Tyrosine-protein kinase BTK  |
Name:  N-[3-[[2-[4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide
Formula:  C28H29N7O2
Similarity:  0.6528925619834711
Relative Targets:   Tyrosine-protein kinase JAK3  |
Name:  N-[3-[5-chloro-2-[4-[(4-methylpiperazin-1-yl)methyl]anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C25H27ClN6O2
Similarity:  0.646551724137931
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[2-(4-morpholinoanilino)pyrimidin-4-yl]phenyl]prop-2-enamide
Formula:  C23H23N5O2
Similarity:  0.6454545454545455
Relative Targets:   Tyrosine-protein kinase JAK3  |
Name:  N-[3-[5-chloro-2-[4-(4-methylpiperazine-1-carbonyl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C25H25ClN6O3
Similarity:  0.635593220338983
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[2-[5-Chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C24H25ClN6O2
Similarity:  0.6347826086956522
Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  | Dual specificity mitogen-activated protein kinase kinase 1  |
Name:  N-[2-[5-Methyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C25H28N6O2
Similarity:  0.6347826086956522
Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  | Dual specificity mitogen-activated protein kinase kinase 1  |
Name:  N-[3-[3-methyl-7-[4-(4-methylpiperazin-1-yl)anilino]-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide
Formula:  C27H30N8O2
Similarity:  0.6311475409836066
Relative Targets:   Epidermal growth factor receptor  |