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Approved Drugs

Name:  Olmutinib

Formula:  C26H26N6O2S

Similarity:  0.518796992481203

Inhibitors

Name:  WZ4002

Formula:  C25H27ClN6O3

Similarity:  0.8018018018018018

Relative Targets:   Epidermal growth factor receptor  | Dipeptidyl peptidase 1  |

Name:  N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]sulfanylphenyl]prop-2-enamide

Formula:  C25H27ClN6O2S

Similarity:  0.8018018018018018

Relative Targets:   Epidermal growth factor receptor  |

Name:  [2-[[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]phenyl] prop-2-enoate

Formula:  C25H27ClN6O3

Similarity:  0.7241379310344828

Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  |

Name:  Rociletinib

Formula:  C27H28F3N7O3

Similarity:  0.7235772357723578

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C26H30N8O3

Similarity:  0.7166666666666667

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]-methyl-carbamoyl]amino]phenyl]prop-2-enamide

Formula:  C27H32N8O3

Similarity:  0.7049180327868853

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[2-chloro-3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxy-phenyl]prop-2-enamide

Formula:  C25H26Cl2N6O3

Similarity:  0.6974789915966386

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxy-2-fluoro-phenyl]prop-2-enamide

Formula:  C25H26ClFN6O3

Similarity:  0.6974789915966386

Relative Targets:   Epidermal growth factor receptor  |

Name:  2-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]-2-methyl-N-[3-(prop-2-enoylamino)phenyl]propanamide

Formula:  C29H35N7O3

Similarity:  0.6935483870967742

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-[2-Methoxy-4-(4-methylpiperazin-1-yl)anilino]-7-oxopyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide

Formula:  C28H29N7O3

Similarity:  0.6854838709677419

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C27H28N8O3

Similarity:  0.6854838709677419

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxy-5-fluoro-phenyl]prop-2-enamide

Formula:  C25H26ClFN6O3

Similarity:  0.6833333333333333

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[3-chloro-6-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-2-pyridyl]oxy]phenyl]prop-2-enamide

Formula:  C26H28ClN5O3

Similarity:  0.680672268907563

Relative Targets:   Dipeptidyl peptidase 1  |

Name:  2-[3-[[2-[4-(4-acetylpiperazin-1-yl)-2-methoxy-anilino]-5-chloro-pyrimidin-4-yl]amino]anilino]ethanesulfonyl fluoride

Formula:  C25H29ClFN7O4S

Similarity:  0.68

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-[2-Methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxopyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide

Formula:  C29H31N7O3

Similarity:  0.6746031746031746

Relative Targets:   Epidermal growth factor receptor  | Tyrosine-protein kinase JAK3  |

Name:  N-[3-[7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide

Formula:  C28H32N8O3

Similarity:  0.6746031746031746

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-6,7-dioxo-5H-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C27H28N8O4

Similarity:  0.6746031746031746

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-3-cyclopropylprop-2-enamide

Formula:  C28H31ClN6O3

Similarity:  0.672

Relative Targets:   Epidermal growth factor receptor  |