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Approved Drugs
Inhibitors
Name:  WZ4002
Formula:  C25H27ClN6O3
Similarity:  0.8018018018018018
Relative Targets:   Epidermal growth factor receptor  | Dipeptidyl peptidase 1  |
Name:  N-[3-[[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide
Formula:  C25H28ClN7O2
Similarity:  0.8018018018018018
Relative Targets:   Epidermal growth factor receptor  |
Name:  Jak3-IN-1
Formula:  C26H30ClN7O2
Similarity:  0.7807017543859649
Relative Targets:   Serine/threonine-protein kinase Sgk1  | Epidermal growth factor receptor  | Platelet-derived growth factor receptor beta  | Tyrosine-protein kinase JAK1  | Non-receptor tyrosine-protein kinase TYK2  | Dual specificity protein kinase TTK  | Receptor-type tyrosine-protein kinase FLT3  | Tyrosine-protein kinase Blk  | Tyrosine-protein kinase JAK3  | Focal adhesion kinase 1  | Tyrosine-protein kinase BTK  | Tyrosine-protein kinase ITK/TSK  | Receptor tyrosine-protein kinase erbB-4  |
Name:  N-[3-[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]sulfanylphenyl]prop-2-enamide
Formula:  C24H25ClN6OS
Similarity:  0.7727272727272727
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[2-chloro-3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxy-phenyl]prop-2-enamide
Formula:  C25H26Cl2N6O3
Similarity:  0.6974789915966386
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxy-2-fluoro-phenyl]prop-2-enamide
Formula:  C25H26ClFN6O3
Similarity:  0.6974789915966386
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[2-[2-Methoxy-4-(4-methylpiperazin-1-yl)anilino]-7-oxopyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide
Formula:  C28H29N7O3
Similarity:  0.6854838709677419
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide
Formula:  C27H28N8O3
Similarity:  0.6854838709677419
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxy-5-fluoro-phenyl]prop-2-enamide
Formula:  C25H26ClFN6O3
Similarity:  0.6833333333333333
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[[3-chloro-6-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-2-pyridyl]oxy]phenyl]prop-2-enamide
Formula:  C26H28ClN5O3
Similarity:  0.680672268907563
Relative Targets:   Dipeptidyl peptidase 1  |
Name:  N-[3-[2-[2-Methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxopyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide
Formula:  C29H31N7O3
Similarity:  0.6746031746031746
Relative Targets:   Epidermal growth factor receptor  | Tyrosine-protein kinase JAK3  |
Name:  N-[3-[7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide
Formula:  C28H32N8O3
Similarity:  0.6746031746031746
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-6,7-dioxo-5H-pteridin-8-yl]phenyl]prop-2-enamide
Formula:  C27H28N8O4
Similarity:  0.6746031746031746
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-3-cyclopropylprop-2-enamide
Formula:  C28H31ClN6O3
Similarity:  0.672
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide
Formula:  C29H31N7O3
Similarity:  0.6692913385826772
Relative Targets:   Tyrosine-protein kinase JAK3  |
Name:  N-[3-[5-chloro-2-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)-1-piperidyl]anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C30H36ClN7O3
Similarity:  0.6641221374045801
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-6,7-dioxo-pteridin-8-yl]phenyl]prop-2-enamide
Formula:  C28H30N8O4
Similarity:  0.6640625
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide
Formula:  C26H30N8O3
Similarity:  0.6612903225806451
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide
Formula:  C30H33N7O3
Similarity:  0.6589147286821705
Relative Targets:   Tyrosine-protein kinase JAK3  |