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Approved Drugs
Inhibitors
Name:  N-[3-[5-chloro-2-[4-[(4-methylpiperazin-1-yl)methyl]-2-(trifluoromethyl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C26H26ClF3N6O2
Similarity:  0.8347826086956521
Relative Targets:   Epidermal growth factor receptor  |
Name:  WZ4002
Formula:  C25H27ClN6O3
Similarity:  0.8053097345132744
Relative Targets:   Epidermal growth factor receptor  | Dipeptidyl peptidase 1  |
Name:  N-[3-[2-[4-(4-methylpiperazin-1-yl)anilino]-5-(trifluoromethyl)pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C25H25F3N6O2
Similarity:  0.7606837606837606
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C24H25ClN6O2
Similarity:  0.7456140350877193
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[2-[4-(4-acetylpiperazin-1-yl)-2-methoxy-anilino]-5-(trifluoromethyl)pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C27H27F3N6O4
Similarity:  0.7142857142857143
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[[6-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-3-(trifluoromethyl)-2-pyridyl]oxy]phenyl]prop-2-enamide
Formula:  C27H28F3N5O3
Similarity:  0.7016129032258065
Relative Targets:   Dipeptidyl peptidase 1  |
Name:  (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-3-cyclopropylprop-2-enamide
Formula:  C28H31ClN6O3
Similarity:  0.6771653543307087
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxy-5-fluoro-phenyl]prop-2-enamide
Formula:  C25H26ClFN6O3
Similarity:  0.6747967479674797
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazine-1-carbonyl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C26H27ClN6O4
Similarity:  0.672
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[5-chloro-2-(2-methoxy-4-morpholino-anilino)pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C24H24ClN5O4
Similarity:  0.6694214876033058
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[5-chloro-2-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)-1-piperidyl]anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C30H36ClN7O3
Similarity:  0.6691729323308271
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[5-chloro-2-[4-(4-hydroxy-1-piperidyl)-2-methoxy-anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C25H26ClN5O4
Similarity:  0.6585365853658537
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]sulfanylphenyl]prop-2-enamide
Formula:  C25H27ClN6O2S
Similarity:  0.6585365853658537
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide
Formula:  C25H28ClN7O2
Similarity:  0.6585365853658537
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[[3-chloro-6-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-2-pyridyl]oxy]phenyl]prop-2-enamide
Formula:  C26H28ClN5O3
Similarity:  0.6585365853658537
Relative Targets:   Dipeptidyl peptidase 1  |
Name:  N-[3-[5-bromo-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C24H25BrN6O2
Similarity:  0.6583333333333333
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxy-2-fluoro-phenyl]prop-2-enamide
Formula:  C25H26ClFN6O3
Similarity:  0.648
Relative Targets:   Epidermal growth factor receptor  |
Name:  Jak3-IN-1
Formula:  C26H30ClN7O2
Similarity:  0.6428571428571429
Relative Targets:   Serine/threonine-protein kinase Sgk1  | Epidermal growth factor receptor  | Platelet-derived growth factor receptor beta  | Tyrosine-protein kinase JAK1  | Non-receptor tyrosine-protein kinase TYK2  | Dual specificity protein kinase TTK  | Receptor-type tyrosine-protein kinase FLT3  | Tyrosine-protein kinase Blk  | Tyrosine-protein kinase JAK3  | Focal adhesion kinase 1  | Tyrosine-protein kinase BTK  | Tyrosine-protein kinase ITK/TSK  | Receptor tyrosine-protein kinase erbB-4  |
Name:  N-[3-[5-chloro-2-[4-[(4-methylpiperazin-1-yl)methyl]anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C25H27ClN6O2
Similarity:  0.6422764227642277
Relative Targets:   Epidermal growth factor receptor  |