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Approved Drugs
Inhibitors
Name:  N-[3-[5-chloro-2-[4-[(4-methylpiperazin-1-yl)methyl]anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C25H27ClN6O2
Similarity:  0.8952380952380953
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[5-chloro-2-[4-[2-(4-methylpiperazin-1-yl)-2-oxo-ethyl]anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C26H27ClN6O3
Similarity:  0.8053097345132744
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C24H25ClN6O2
Similarity:  0.7981651376146789
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[5-chloro-2-[4-(4-methylpiperazine-1-carbonyl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C25H25ClN6O3
Similarity:  0.7631578947368421
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[5-bromo-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C24H25BrN6O2
Similarity:  0.7043478260869566
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[5-chloro-2-[4-[(4-methylpiperazin-1-yl)methyl]-2-(trifluoromethyl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C26H26ClF3N6O2
Similarity:  0.6910569105691057
Relative Targets:   Epidermal growth factor receptor  |
Name:  4-[[5-chloro-4-[3-(prop-2-enoylamino)phenoxy]pyrimidin-2-yl]amino]-N-(1-methyl-4-piperidyl)benzamide
Formula:  C26H27ClN6O3
Similarity:  0.6721311475409836
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[2-[4-(4-methylpiperazin-1-yl)anilino]-5-(trifluoromethyl)pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C25H25F3N6O2
Similarity:  0.6639344262295082
Relative Targets:   Epidermal growth factor receptor  |
Name:  WZ4002
Formula:  C25H27ClN6O3
Similarity:  0.6475409836065574
Relative Targets:   Epidermal growth factor receptor  | Dipeptidyl peptidase 1  |
Name:  N-[3-[[3-chloro-6-[4-(4-methylpiperazin-1-yl)anilino]-2-pyridyl]oxy]phenyl]prop-2-enamide
Formula:  C25H26ClN5O2
Similarity:  0.6470588235294118
Relative Targets:   Dipeptidyl peptidase 1  |
Name:  N-[2-[5-Chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C24H25ClN6O2
Similarity:  0.6333333333333333
Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  | Dual specificity mitogen-activated protein kinase kinase 1  |
Name:  N-[3-[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]sulfanylphenyl]prop-2-enamide
Formula:  C24H25ClN6OS
Similarity:  0.6333333333333333
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C24H26N6O2
Similarity:  0.6302521008403361
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[5-chloro-2-[4-(4-methylpiperazin-1-yl)-2-(trifluoromethyl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C25H24ClF3N6O2
Similarity:  0.626984126984127
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[[2-[4-(4-methylpiperazin-1-yl)anilino]-9H-purin-6-yl]oxy]phenyl]prop-2-enamide
Formula:  C25H26N8O2
Similarity:  0.624
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazine-1-carbonyl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C26H27ClN6O4
Similarity:  0.6220472440944882
Relative Targets:   Epidermal growth factor receptor  |
Name:  Olmutinib
Formula:  C26H26N6O2S
Similarity:  0.6111111111111112
Relative Targets:   Tyrosine-protein kinase BTK  |
Name:  N-[3-[[2-[4-(4-Methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide
Formula:  C26H27N7O2
Similarity:  0.6111111111111112
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[[2-[3-chloro-4-(4-methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide
Formula:  C26H26ClN7O2
Similarity:  0.6015625
Relative Targets:   Epidermal growth factor receptor  |