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Approved Drugs

Name:  Olmutinib

Formula:  C26H26N6O2S

Similarity:  0.5035971223021583

Inhibitors

Name:  N-[3-[5-chloro-2-[4-(4-methylpiperazin-1-yl)-2-(trifluoromethyl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C25H24ClF3N6O2

Similarity:  0.8347826086956521

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-chloro-2-[4-[(4-methylpiperazin-1-yl)methyl]anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C25H27ClN6O2

Similarity:  0.7521367521367521

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-chloro-2-[4-[2-(4-methylpiperazin-1-yl)ethyl]anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C26H29ClN6O2

Similarity:  0.6910569105691057

Relative Targets:   Epidermal growth factor receptor  |

Name:  WZ4002

Formula:  C25H27ClN6O3

Similarity:  0.6829268292682927

Relative Targets:   Epidermal growth factor receptor  | Dipeptidyl peptidase 1  |

Name:  N-[3-[2-[4-(4-methylpiperazin-1-yl)anilino]-5-(trifluoromethyl)pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C25H25F3N6O2

Similarity:  0.6587301587301587

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazine-1-carbonyl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C26H27ClN6O4

Similarity:  0.65625

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C24H25ClN6O2

Similarity:  0.6422764227642277

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-chloro-2-[4-[2-(4-methylpiperazin-1-yl)-2-oxo-ethyl]anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C26H27ClN6O3

Similarity:  0.640625

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-chloro-2-[2-methoxy-4-(1-methyl-4-piperidyl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C26H28ClN5O3

Similarity:  0.6171875

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-chloro-2-[4-(4-methylpiperazine-1-carbonyl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C25H25ClN6O3

Similarity:  0.6171875

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-[4-(4-acetylpiperazin-1-yl)-2-methoxy-anilino]-5-(trifluoromethyl)pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C27H27F3N6O4

Similarity:  0.6102941176470589

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[6-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-3-(trifluoromethyl)-2-pyridyl]oxy]phenyl]prop-2-enamide

Formula:  C27H28F3N5O3

Similarity:  0.5970149253731343

Relative Targets:   Dipeptidyl peptidase 1  |

Name:  N-[3-[5-chloro-2-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)-1-piperidyl]anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C30H36ClN7O3

Similarity:  0.5957446808510638

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-chloro-2-[2-methoxy-4-(1-methyl-3-piperidyl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C26H28ClN5O3

Similarity:  0.5923076923076923

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-chloro-2-(2-methoxy-4-morpholino-anilino)pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C24H24ClN5O4

Similarity:  0.5891472868217055

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-chloro-2-(4-fluoro-2-methoxy-anilino)pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C20H16ClFN4O3

Similarity:  0.5882352941176471

Relative Targets:   Epidermal growth factor receptor  |

Name:  4-[[5-chloro-4-[3-(prop-2-enoylamino)phenoxy]pyrimidin-2-yl]amino]-3-methoxy-N-(1-methyl-4-piperidyl)benzamide

Formula:  C27H29ClN6O4

Similarity:  0.5808823529411765

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-chloro-2-[4-(4-hydroxy-1-piperidyl)-2-methoxy-anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C25H26ClN5O4

Similarity:  0.5801526717557252

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-chloro-2-[2-methoxy-4-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C26H26ClN5O3

Similarity:  0.5801526717557252

Relative Targets:   Epidermal growth factor receptor  |