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Approved Drugs

Name:  Olmutinib

Formula:  C26H26N6O2S

Similarity:  0.5413533834586466

Inhibitors

Name:  4-[[5-chloro-4-[3-(prop-2-enoylamino)phenoxy]pyrimidin-2-yl]amino]-3-methoxy-N-(1-methyl-4-piperidyl)benzamide

Formula:  C27H29ClN6O4

Similarity:  0.788135593220339

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-chloro-2-[4-(4-methylpiperazine-1-carbonyl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C25H25ClN6O3

Similarity:  0.7652173913043478

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C24H25ClN6O2

Similarity:  0.7068965517241379

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-chloro-2-[4-[2-(4-methylpiperazin-1-yl)-2-oxo-ethyl]anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C26H27ClN6O3

Similarity:  0.7024793388429752

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-chloro-2-[4-[(4-methylpiperazin-1-yl)methyl]anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C25H27ClN6O2

Similarity:  0.6890756302521008

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-chloro-2-[4-[2-(4-methylpiperazin-1-yl)ethyl]anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C26H29ClN6O2

Similarity:  0.6721311475409836

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-chloro-2-[2-methoxy-4-(1-methyl-4-piperidyl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C26H28ClN5O3

Similarity:  0.6370967741935484

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-bromo-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C24H25BrN6O2

Similarity:  0.6229508196721312

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazine-1-carbonyl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C26H27ClN6O4

Similarity:  0.6124031007751938

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-[4-(4-methylpiperazin-1-yl)anilino]-5-(trifluoromethyl)pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C25H25F3N6O2

Similarity:  0.5891472868217055

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[5-Acetamido-2-[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C26H28ClN7O3

Similarity:  0.5757575757575758

Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  | Dual specificity mitogen-activated protein kinase kinase 1  |

Name:  WZ4002

Formula:  C25H27ClN6O3

Similarity:  0.5736434108527132

Relative Targets:   Epidermal growth factor receptor  | Dipeptidyl peptidase 1  |

Name:  N-[3-[5-chloro-2-[4-(4-hydroxy-1-piperidyl)-2-methoxy-anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C25H26ClN5O4

Similarity:  0.5736434108527132

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-chloro-2-[2-methoxy-4-(1-methyl-3-piperidyl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C26H28ClN5O3

Similarity:  0.5736434108527132

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[3-chloro-6-[4-(4-methylpiperazin-1-yl)anilino]-2-pyridyl]oxy]phenyl]prop-2-enamide

Formula:  C25H26ClN5O2

Similarity:  0.5714285714285714

Relative Targets:   Dipeptidyl peptidase 1  |

Name:  4-[[5-chloro-4-[3-(prop-2-enoylamino)phenoxy]pyrimidin-2-yl]amino]-3-methoxy-N-(2-morpholinoethyl)benzamide

Formula:  C27H29ClN6O5

Similarity:  0.5693430656934306

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[2-[5-Chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C24H25ClN6O2

Similarity:  0.5590551181102362

Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  | Dual specificity mitogen-activated protein kinase kinase 1  |

Name:  N-[3-[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]sulfanylphenyl]prop-2-enamide

Formula:  C24H25ClN6OS

Similarity:  0.5590551181102362

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[4-(1-methyl-4-piperidyl)anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C26H29N7O2

Similarity:  0.5572519083969466

Relative Targets:   Epidermal growth factor receptor  |