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Approved Drugs
Inhibitors
Name:  WZ4002
Formula:  C25H27ClN6O3
Similarity:  0.8141592920353983
Relative Targets:   Epidermal growth factor receptor  | Dipeptidyl peptidase 1  |
Name:  N-[3-[5-chloro-2-[4-(4-methylpiperazine-1-carbonyl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C25H25ClN6O3
Similarity:  0.782608695652174
Relative Targets:   Epidermal growth factor receptor  |
Name:  4-[[5-chloro-4-[3-(prop-2-enoylamino)phenoxy]pyrimidin-2-yl]amino]-3-methoxy-N-(1-methyl-4-piperidyl)benzamide
Formula:  C27H29ClN6O4
Similarity:  0.775
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[5-chloro-2-[2-methoxy-4-(1-methyl-4-piperidyl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C26H28ClN5O3
Similarity:  0.7372881355932204
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[5-chloro-2-[2-methoxy-4-(1-methyl-3-piperidyl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C26H28ClN5O3
Similarity:  0.7083333333333334
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[5-chloro-2-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)-1-piperidyl]anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C30H36ClN7O3
Similarity:  0.7022900763358778
Relative Targets:   Epidermal growth factor receptor  |
Name:  4-[[5-chloro-4-[3-(prop-2-enoylamino)phenoxy]pyrimidin-2-yl]amino]-3-methoxy-N-(2-morpholinoethyl)benzamide
Formula:  C27H29ClN6O5
Similarity:  0.6953125
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[5-chloro-2-[2-methoxy-4-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C26H26ClN5O3
Similarity:  0.6942148760330579
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[5-chloro-2-(2-methoxy-4-morpholino-anilino)pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C24H24ClN5O4
Similarity:  0.6916666666666667
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[5-chloro-2-[4-[2-(4-methylpiperazin-1-yl)-2-oxo-ethyl]anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C26H27ClN6O3
Similarity:  0.6910569105691057
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-3-cyclopropylprop-2-enamide
Formula:  C28H31ClN6O3
Similarity:  0.6850393700787402
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[5-chloro-2-(4-fluoro-2-methoxy-anilino)pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C20H16ClFN4O3
Similarity:  0.6846846846846847
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[5-chloro-2-[4-(4-hydroxy-1-piperidyl)-2-methoxy-anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C25H26ClN5O4
Similarity:  0.680327868852459
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[[2-[2-methoxy-4-(4-methylpiperazine-1-carbonyl)anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide
Formula:  C27H30N8O4
Similarity:  0.6744186046511628
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[5-chloro-2-[4-(4-methylpiperazin-1-yl)-2-(trifluoromethyl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C25H24ClF3N6O2
Similarity:  0.672
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxy-5-fluoro-phenyl]prop-2-enamide
Formula:  C25H26ClFN6O3
Similarity:  0.6693548387096774
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[2-[4-(4-acetylpiperazin-1-yl)-2-methoxy-anilino]-5-(trifluoromethyl)pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C27H27F3N6O4
Similarity:  0.6692307692307692
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[[3-chloro-6-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-2-pyridyl]oxy]phenyl]prop-2-enamide
Formula:  C26H28ClN5O3
Similarity:  0.6666666666666666
Relative Targets:   Dipeptidyl peptidase 1  |
Name:  N-[3-[5-chloro-2-[4-[(4-methylpiperazin-1-yl)methyl]-2-(trifluoromethyl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C26H26ClF3N6O2
Similarity:  0.65625
Relative Targets:   Epidermal growth factor receptor  |