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Approved Drugs
Inhibitors
Name:  N-[3-[5-bromo-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C24H25BrN6O2
Similarity:  0.8811881188118812
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[2-[4-(4-methylpiperazin-1-yl)anilino]-5-(trifluoromethyl)pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C25H25F3N6O2
Similarity:  0.8240740740740741
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[5-chloro-2-[4-[(4-methylpiperazin-1-yl)methyl]anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C25H27ClN6O2
Similarity:  0.8207547169811321
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[[3-chloro-6-[4-(4-methylpiperazin-1-yl)anilino]-2-pyridyl]oxy]phenyl]prop-2-enamide
Formula:  C25H26ClN5O2
Similarity:  0.8095238095238095
Relative Targets:   Dipeptidyl peptidase 1  |
Name:  N-[3-[5-chloro-2-[4-(4-methylpiperazine-1-carbonyl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C25H25ClN6O3
Similarity:  0.8055555555555556
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[5-chloro-2-[4-[2-(4-methylpiperazin-1-yl)ethyl]anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C26H29ClN6O2
Similarity:  0.7981651376146789
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[2-[5-Chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C24H25ClN6O2
Similarity:  0.7924528301886793
Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  | Dual specificity mitogen-activated protein kinase kinase 1  |
Name:  N-[3-[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]sulfanylphenyl]prop-2-enamide
Formula:  C24H25ClN6OS
Similarity:  0.7924528301886793
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C24H26N6O2
Similarity:  0.7904761904761904
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[5-chloro-2-[4-[2-(4-methylpiperazin-1-yl)-2-oxo-ethyl]anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C26H27ClN6O3
Similarity:  0.7837837837837838
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[[2-[4-(4-methylpiperazin-1-yl)anilino]-9H-purin-6-yl]oxy]phenyl]prop-2-enamide
Formula:  C25H26N8O2
Similarity:  0.7747747747747747
Relative Targets:   Epidermal growth factor receptor  |
Name:  WZ4002
Formula:  C25H27ClN6O3
Similarity:  0.7727272727272727
Relative Targets:   Epidermal growth factor receptor  | Dipeptidyl peptidase 1  |
Name:  Olmutinib
Formula:  C26H26N6O2S
Similarity:  0.7589285714285714
Relative Targets:   Tyrosine-protein kinase BTK  |
Name:  N-[3-[[2-[4-(4-Methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide
Formula:  C26H27N7O2
Similarity:  0.7589285714285714
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[5-chloro-2-[4-(4-methylpiperazin-1-yl)-2-(trifluoromethyl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C25H24ClF3N6O2
Similarity:  0.7456140350877193
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[5-Acetamido-2-[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C26H28ClN7O3
Similarity:  0.7391304347826086
Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  | Dual specificity mitogen-activated protein kinase kinase 1  |
Name:  4-[[5-chloro-4-[3-(prop-2-enoylamino)phenoxy]pyrimidin-2-yl]amino]-N-(1-methyl-4-piperidyl)benzamide
Formula:  C26H27ClN6O3
Similarity:  0.7068965517241379
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[2-[[5-Chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide
Formula:  C24H26ClN7O
Similarity:  0.6964285714285714
Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  | Dual specificity mitogen-activated protein kinase kinase 1  |
Name:  N-[2-[5-Chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]sulfanylphenyl]prop-2-enamide
Formula:  C24H25ClN6OS
Similarity:  0.6964285714285714
Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  | Dual specificity mitogen-activated protein kinase kinase 1  |