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Approved Drugs

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Inhibitors

Name:  N-[3-[5-chloro-2-[2-methoxy-4-(1-methyl-4-piperidyl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C26H28ClN5O3

Similarity:  0.8518518518518519

Relative Targets:   Epidermal growth factor receptor  |

Name:  WZ4002

Formula:  C25H27ClN6O3

Similarity:  0.7391304347826086

Relative Targets:   Epidermal growth factor receptor  | Dipeptidyl peptidase 1  |

Name:  N-[3-[5-chloro-2-[4-(4-hydroxy-1-piperidyl)-2-methoxy-anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C25H26ClN5O4

Similarity:  0.7241379310344828

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-chloro-2-[2-methoxy-4-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C26H26ClN5O3

Similarity:  0.7241379310344828

Relative Targets:   Epidermal growth factor receptor  |

Name:  4-[[5-chloro-4-[3-(prop-2-enoylamino)phenoxy]pyrimidin-2-yl]amino]-3-methoxy-N-(1-methyl-4-piperidyl)benzamide

Formula:  C27H29ClN6O4

Similarity:  0.71900826446281

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-chloro-2-(4-fluoro-2-methoxy-anilino)pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C20H16ClFN4O3

Similarity:  0.7169811320754716

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazine-1-carbonyl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C26H27ClN6O4

Similarity:  0.7083333333333334

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-chloro-2-(2-methoxy-4-morpholino-anilino)pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C24H24ClN5O4

Similarity:  0.7068965517241379

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-chloro-2-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)-1-piperidyl]anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C30H36ClN7O3

Similarity:  0.6641221374045801

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-3-cyclopropylprop-2-enamide

Formula:  C28H31ClN6O3

Similarity:  0.6456692913385826

Relative Targets:   Epidermal growth factor receptor  |

Name:  4-[[5-chloro-4-[3-(prop-2-enoylamino)phenoxy]pyrimidin-2-yl]amino]-3-methoxy-N-(2-morpholinoethyl)benzamide

Formula:  C27H29ClN6O5

Similarity:  0.6307692307692307

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-chloro-2-[2-methoxy-4-(4-pyridyl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C25H20ClN5O3

Similarity:  0.6229508196721312

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-chloro-2-[4-(4-methylpiperazin-1-yl)-2-(trifluoromethyl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C25H24ClF3N6O2

Similarity:  0.6062992125984252

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxy-5-fluoro-phenyl]prop-2-enamide

Formula:  C25H26ClFN6O3

Similarity:  0.6031746031746031

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[3-chloro-6-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-2-pyridyl]oxy]phenyl]prop-2-enamide

Formula:  C26H28ClN5O3

Similarity:  0.6

Relative Targets:   Dipeptidyl peptidase 1  |

Name:  (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-cyclopropylprop-2-enamide

Formula:  C29H30ClN7O3

Similarity:  0.5970149253731343

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-2-cyano-N-(2-hydroxy-1,1-dimethyl-ethyl)-3-[3-(3,4,5-trimethoxyphenyl)-1H-indazol-5-yl]prop-2-enamide

Formula:  C29H30ClN7O3

Similarity:  0.5970149253731343

Relative Targets:   Ribosomal protein S6 kinase alpha-3  |

Name:  N-[3-[5-chloro-2-[4-[(4-methylpiperazin-1-yl)methyl]-2-(trifluoromethyl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C26H26ClF3N6O2

Similarity:  0.5923076923076923

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]sulfanylphenyl]prop-2-enamide

Formula:  C25H27ClN6O2S

Similarity:  0.5873015873015873

Relative Targets:   Epidermal growth factor receptor  |