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Approved Drugs
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Inhibitors
Name:  (2S)-N-[4-(3-chloro-2-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-1-prop-2-enoyl-pyrrolidine-2-carboxamide
Formula:  C25H25ClFN5O4
Similarity:  0.8392857142857143
Relative Targets:   Tyrosine-protein kinase ABL1  | Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Tyrosine-protein kinase Lck  | Proto-oncogene tyrosine-protein kinase receptor Ret  | Insulin-like growth factor 1 receptor  | Hepatocyte growth factor receptor  | Platelet-derived growth factor receptor beta  | Mast/stem cell growth factor receptor Kit  | Fibroblast growth factor receptor 1  | Proto-oncogene tyrosine-protein kinase Src  | Platelet-derived growth factor receptor alpha  | Vascular endothelial growth factor receptor 1  | Fibroblast growth factor receptor 2  | Cyclin-dependent kinase 2  | Mitogen-activated protein kinase 1  | RAC-alpha serine/threonine-protein kinase  | Vascular endothelial growth factor receptor 3  | Vascular endothelial growth factor receptor 2  | Receptor-type tyrosine-protein kinase FLT3  | Receptor tyrosine-protein kinase erbB-4  |
Name:  N-[4-(3-cyano-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]prop-2-enamide
Formula:  C21H18FN5O3
Similarity:  0.5365853658536586
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[4-[4-chloro-3-(trifluoromethyl)anilino]-7-(2-methoxyethoxy)quinazolin-6-yl]prop-2-enamide
Formula:  C21H18ClF3N4O3
Similarity:  0.5196850393700787
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(1-piperidyl)but-2-enamide
Formula:  C26H29ClFN5O3
Similarity:  0.5182481751824818
Relative Targets:   Epidermal growth factor receptor  |
Name:  1-[4-[4-(3,4-dichloro-2-fluoro-anilino)-7-methoxy-quinazolin-6-yl]oxy-1-piperidyl]prop-2-en-1-one
Formula:  C23H21Cl2FN4O3
Similarity:  0.5153846153846153
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-[cyclopropyl(methyl)amino]but-2-enamide
Formula:  C25H27ClFN5O3
Similarity:  0.5149253731343284
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[4-[[7-(2-methoxyethoxy)-6-(prop-2-enoylamino)quinazolin-4-yl]amino]-2-(trifluoromethyl)phenyl]prop-2-enamide
Formula:  C24H22F3N5O4
Similarity:  0.5111111111111111
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dicyclopropylamino)but-2-enamide
Formula:  C27H29ClFN5O3
Similarity:  0.5035971223021583
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(1-oxidothiomorpholin-1-ium-4-yl)but-2-enamide
Formula:  C25H27ClFN5O4S
Similarity:  0.5
Relative Targets:   Epidermal growth factor receptor  |