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Approved Drugs
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Inhibitors
Name:  (2S)-N-[4-(3-chloro-2,4-difluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-1-prop-2-enoyl-pyrrolidine-2-carboxamide
Formula:  C25H24ClF2N5O4
Similarity:  0.8392857142857143
Relative Targets:   Tyrosine-protein kinase ABL1  | Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Tyrosine-protein kinase Lck  | Proto-oncogene tyrosine-protein kinase receptor Ret  | Insulin-like growth factor 1 receptor  | Hepatocyte growth factor receptor  | Platelet-derived growth factor receptor beta  | Mast/stem cell growth factor receptor Kit  | Fibroblast growth factor receptor 1  | Proto-oncogene tyrosine-protein kinase Src  | Platelet-derived growth factor receptor alpha  | Vascular endothelial growth factor receptor 1  | Fibroblast growth factor receptor 2  | Cyclin-dependent kinase 2  | Mitogen-activated protein kinase 1  | RAC-alpha serine/threonine-protein kinase  | Vascular endothelial growth factor receptor 3  | Vascular endothelial growth factor receptor 2  | Receptor-type tyrosine-protein kinase FLT3  | Receptor tyrosine-protein kinase erbB-4  |
Name:  N-[4-[4-chloro-3-(trifluoromethyl)anilino]-7-(2-methoxyethoxy)quinazolin-6-yl]prop-2-enamide
Formula:  C21H18ClF3N4O3
Similarity:  0.5403225806451613
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[4-(3-chloro-2-fluoro-anilino)-7-[[1-[3-(hydroxyamino)-3-oxo-propyl]triazol-4-yl]methoxy]quinazolin-6-yl]prop-2-enamide
Formula:  C23H20ClFN8O4
Similarity:  0.5333333333333333
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[4-(3-cyano-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]prop-2-enamide
Formula:  C21H18FN5O3
Similarity:  0.5327868852459017
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[4-(3-ethynylanilino)-7-(2-methoxyethoxy)quinazolin-6-yl]prop-2-enamide
Formula:  C22H20N4O3
Similarity:  0.5289256198347108
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(1-piperidyl)but-2-enamide
Formula:  C26H29ClFN5O3
Similarity:  0.5259259259259259
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-[cyclopropyl(methyl)amino]but-2-enamide
Formula:  C25H27ClFN5O3
Similarity:  0.5227272727272727
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[4-(3-chloro-2-fluoro-anilino)-7-[[1-[4-(hydroxyamino)-4-oxo-butyl]triazol-4-yl]methoxy]quinazolin-6-yl]prop-2-enamide
Formula:  C24H22ClFN8O4
Similarity:  0.5217391304347826
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dicyclopropylamino)but-2-enamide
Formula:  C27H29ClFN5O3
Similarity:  0.5109489051094891
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[4-(3-chloro-2-fluoro-anilino)-7-[[1-[5-(hydroxyamino)-5-oxo-pentyl]triazol-4-yl]methoxy]quinazolin-6-yl]prop-2-enamide
Formula:  C25H24ClFN8O4
Similarity:  0.5106382978723404
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[4-[[7-(2-methoxyethoxy)-6-(prop-2-enoylamino)quinazolin-4-yl]amino]-2-(trifluoromethyl)phenyl]prop-2-enamide
Formula:  C24H22F3N5O4
Similarity:  0.5074626865671642
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-(2-methoxyethoxy)quinazolin-6-yl]prop-2-enamide
Formula:  C27H24ClFN4O4
Similarity:  0.5072463768115942
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(1-oxidothiomorpholin-1-ium-4-yl)but-2-enamide
Formula:  C25H27ClFN5O4S
Similarity:  0.5072463768115942
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula:  C23H25ClFN5O3
Similarity:  0.5
Relative Targets:   Epidermal growth factor receptor  |