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Approved Drugs
Name: Afatinib
Formula: C24H25ClFN5O3
Similarity: 0.5
Inhibitors
Name: (E)-N-[4-(3-bromoanilino)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula: C20H20BrN5O
Similarity: 0.8554216867469879
Relative Targets: Proto-oncogene tyrosine-protein kinase Src | Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-bromoanilino)quinazolin-6-yl]-3-(dimethylamino)prop-2-enamide
Formula: C19H18BrN5O
Similarity: 0.7159090909090909
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: 2-chloro-N-[4-(3-iodoanilino)quinazolin-6-yl]acetamide
Formula: C16H12ClIN4O
Similarity: 0.7023809523809523
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-bromoanilino)quinazolin-6-yl]-4-[2-hydroxyethyl(methyl)amino]but-2-enamide
Formula: C21H22BrN5O2
Similarity: 0.7021276595744681
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-bromoanilino)quinazolin-6-yl]-4-(diethylamino)but-2-enamide
Formula: C22H24BrN5O
Similarity: 0.7021276595744681
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-bromoanilino)quinazolin-6-yl]-4-[2-methoxyethyl(methyl)amino]but-2-enamide
Formula: C22H24BrN5O2
Similarity: 0.6979166666666666
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-bromoanilino)quinazolin-6-yl]-4-methoxy-but-2-enamide
Formula: C19H17BrN4O2
Similarity: 0.6888888888888889
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-bromoanilino)quinazolin-6-yl]but-2-enamide
Formula: C18H15BrN4O
Similarity: 0.6781609195402298
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (Z)-N-[4-(3-bromoanilino)quinazolin-6-yl]but-2-enamide
Formula: C18H15BrN4O
Similarity: 0.6781609195402298
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-bromoanilino)quinazolin-6-yl]-4-(dipropylamino)but-2-enamide
Formula: C24H28BrN5O
Similarity: 0.66
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: N-[4-(3-methylanilino)quinazolin-6-yl]prop-2-enamide
Formula: C18H16N4O
Similarity: 0.6436781609195402
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-bromoanilino)quinazolin-6-yl]-4-oxo-pent-2-enamide
Formula: C19H15BrN4O2
Similarity: 0.6413043478260869
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N'-[4-(3-bromoanilino)quinazolin-6-yl]-N-[3-(dimethylamino)propyl]but-2-enediamide
Formula: C23H25BrN6O2
Similarity: 0.6310679611650486
Relative Targets: Epidermal growth factor receptor |
Name: 3-(dimethylamino)propyl(E)-4-[[4-(3-bromoanilino)quinazolin-6-yl]amino]-4-oxo-but-2-enoate
Formula: C23H24BrN5O3
Similarity: 0.6310679611650486
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(4,5-dichloro-2-fluoro-anilino)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula: C20H18Cl2FN5O
Similarity: 0.6288659793814433
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Platelet-derived growth factor receptor beta |
Name: N-[4-(3-bromoanilino)quinazolin-6-yl]prop-2-enamide
Formula: C17H13BrN4O
Similarity: 0.625
Relative Targets: Proto-oncogene tyrosine-protein kinase Src | Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Proto-oncogene tyrosine-protein kinase Src |
Name: N-[4-(3-chloroanilino)quinazolin-6-yl]prop-2-enamide
Formula: C17H13ClN4O
Similarity: 0.625
Relative Targets: Epidermal growth factor receptor |
Name: (E)-4-[[4-(3-bromoanilino)quinazolin-6-yl]amino]-4-oxo-but-2-enoicacid
Formula: C18H13BrN4O3
Similarity: 0.6236559139784946
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-bromoanilino)-3-cyano-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C22H20BrN5O
Similarity: 0.6224489795918368
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |