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Name:  Afatinib

Formula:  C₂₄H₂₅ClFN₅O₃

Similarity:  0.5892857142857143

Name:  N-[4-(4,5-dichloro-2-fluoro-anilino)quinazolin-6-yl]prop-2-enamide

Formula:  C₁₇H₁₁Cl₂FN₄O

Similarity:  0.7558139534883721

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)pyrido[3,4-d]pyrimidin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C₁₉H₁₈ClFN₆O

Similarity:  0.6494845360824743

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Receptor tyrosine-protein kinase erbB-4  |

Name:  (E)-N-[4-(3-bromoanilino)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C₂₀H₂₀BrN₅O

Similarity:  0.6288659793814433

Relative Targets:   Proto-oncogene tyrosine-protein kinase Src  | Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-4-(dimethylamino)-N-[4-(3-iodoanilino)quinazolin-6-yl]but-2-enamide

Formula:  C₂₀H₂₀IN₅O

Similarity:  0.6288659793814433

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C₂₃H₂₅ClFN₅O₃

Similarity:  0.6111111111111112

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(1R)-2-methoxy-1-methyl-ethoxy]quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C₂₄H₂₇ClFN₅O₃

Similarity:  0.6

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(1S)-2-methoxy-1-methyl-ethoxy]quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C₂₄H₂₇ClFN₅O₃

Similarity:  0.6

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(3-methoxypropoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C₂₄H₂₇ClFN₅O₃

Similarity:  0.5945945945945946

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-ethoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C₂₄H₂₇ClFN₅O₃

Similarity:  0.5945945945945946

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  Afatinib

Formula:  C₂₄H₂₅ClFN₅O₃

Similarity:  0.5892857142857143

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Dipeptidyl peptidase 1  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-6-[(3R)-tetrahydrofuran-3-yl]oxy-quinazolin-7-yl]-4-(dimethylamino)but-2-enamide

Formula:  C₂₄H₂₅ClFN₅O₃

Similarity:  0.5892857142857143

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-isopropoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C₂₅H₂₉ClFN₅O₃

Similarity:  0.584070796460177

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-propoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C₂₅H₂₉ClFN₅O₃

Similarity:  0.5789473684210527

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-6-quinolyl]-4-(dimethylamino)but-2-enamide

Formula:  C₂₂H₁₉ClFN₅O

Similarity:  0.5714285714285714

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-quinazolin-6-yl]-4-[cyclopropyl(methyl)amino]but-2-enamide

Formula:  C₂₃H₂₃ClFN₅O₂

Similarity:  0.5688073394495413

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(4-bromo-2-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C₂₃H₂₅BrFN₅O₃

Similarity:  0.5675675675675675

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-ethoxy-quinazolin-6-yl]-4-[cyclopropyl(methyl)amino]but-2-enamide

Formula:  C₂₄H₂₅ClFN₅O₂

Similarity:  0.5535714285714286

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-cyano-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C₂₄H₂₅FN₆O₃

Similarity:  0.5526315789473685

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-[4-chloro-3-(trifluoromethyl)anilino]-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C₂₄H₂₅ClF₃N₅O₃

Similarity:  0.5470085470085471

Relative Targets:   Epidermal growth factor receptor  |