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Approved Drugs
Name: Neratinib
Formula: C30H29ClN6O3
Similarity: 0.6343283582089553
Inhibitors
Name: (E)-N-[4-[3-chloro-4-(1-methylimidazol-2-yl)sulfanyl-anilino]-3-cyano-7-methoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C27H26ClN7O2S
Similarity: 0.811965811965812
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-chloro-4-pyrimidin-2-ylsulfanyl-anilino)-3-cyano-7-methoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C27H24ClN7O2S
Similarity: 0.8050847457627118
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-methoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C23H21ClFN5O2
Similarity: 0.7477477477477478
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-[3-chloro-4-(5-phenylthiazol-2-yl)sulfanyl-anilino]-3-cyano-7-methoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C32H27ClN6O2S2
Similarity: 0.7404580152671756
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-chloro-4-imidazol-1-yl-anilino)-3-cyano-7-methoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C26H24ClN7O2
Similarity: 0.725
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-[3-chloro-4-(3-pyridylmethylamino)anilino]-3-cyano-7-methoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C29H28ClN7O2
Similarity: 0.6875
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-bromoanilino)-3-cyano-7-methoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C23H22BrN5O2
Similarity: 0.6842105263157895
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-[3-chloro-4-(4-phenylthiazol-2-yl)sulfanyl-anilino]-3-cyano-7-ethoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C33H29ClN6O2S2
Similarity: 0.6739130434782609
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-ethoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C24H23ClFN5O2
Similarity: 0.6694915254237288
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(4-benzyloxy-3-chloro-anilino)-3-cyano-7-methoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C30H28ClN5O3
Similarity: 0.6615384615384615
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-[4-(benzylamino)-3-chloro-anilino]-3-cyano-7-methoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C30H29ClN6O2
Similarity: 0.6615384615384615
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-[3-chloro-4-(2-thienylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C29H28ClN5O3S
Similarity: 0.648854961832061
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-[4-(anilinomethylamino)-3-chloro-anilino]-3-cyano-7-methoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C30H30ClN7O2
Similarity: 0.6466165413533834
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-[3-chloro-4-[(4-phenylthiazol-2-yl)methyl]anilino]-3-cyano-7-methoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C33H29ClN6O2S
Similarity: 0.6402877697841727
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-methoxy-6-quinolyl]-4-(diethylamino)but-2-enamide
Formula: C25H25ClFN5O2
Similarity: 0.639344262295082
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-[3-chloro-4-[(1-methylimidazol-2-yl)methoxy]anilino]-3-cyano-7-ethoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C29H30ClN7O3
Similarity: 0.6390977443609023
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-[3-chloro-4-(imidazol-1-ylmethyl)anilino]-3-cyano-7-ethoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C28H28ClN7O2
Similarity: 0.6384615384615384
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-[3-chloro-4-(4-pyridyloxy)anilino]-3-cyano-7-ethoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C29H27ClN6O3
Similarity: 0.6363636363636364
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C30H29ClN6O3
Similarity: 0.6343283582089553
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |