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Approved Drugs

Name:  Neratinib

Formula:  C30H29ClN6O3

Similarity:  0.6567164179104478

Inhibitors

Name:  (E)-N-[4-(3-chloro-4-thiazol-2-ylsulfanyl-anilino)-3-cyano-7-methoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide

Formula:  C26H23ClN6O2S2

Similarity:  0.8050847457627118

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-[3-chloro-4-(1-methylimidazol-2-yl)sulfanyl-anilino]-3-cyano-7-methoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide

Formula:  C27H26ClN7O2S

Similarity:  0.7916666666666666

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-methoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide

Formula:  C23H21ClFN5O2

Similarity:  0.7280701754385965

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-chloro-4-imidazol-1-yl-anilino)-3-cyano-7-methoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide

Formula:  C26H24ClN7O2

Similarity:  0.7213114754098361

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-[3-chloro-4-(5-phenylthiazol-2-yl)sulfanyl-anilino]-3-cyano-7-methoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide

Formula:  C32H27ClN6O2S2

Similarity:  0.7111111111111111

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-[3-chloro-4-(3-pyridylmethylamino)anilino]-3-cyano-7-methoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide

Formula:  C29H28ClN7O2

Similarity:  0.6976744186046512

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-bromoanilino)-3-cyano-7-methoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide

Formula:  C23H22BrN5O2

Similarity:  0.6810344827586207

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(4-benzyloxy-3-chloro-anilino)-3-cyano-7-methoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide

Formula:  C30H28ClN5O3

Similarity:  0.6717557251908397

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-[4-(benzylamino)-3-chloro-anilino]-3-cyano-7-methoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide

Formula:  C30H29ClN6O2

Similarity:  0.6717557251908397

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-[4-(anilinomethylamino)-3-chloro-anilino]-3-cyano-7-methoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide

Formula:  C30H30ClN7O2

Similarity:  0.6567164179104478

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide

Formula:  C30H29ClN6O3

Similarity:  0.6567164179104478

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-ethoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide

Formula:  C24H23ClFN5O2

Similarity:  0.6528925619834711

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-[3-chloro-4-(4-pyridyloxy)anilino]-3-cyano-7-ethoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide

Formula:  C29H27ClN6O3

Similarity:  0.6466165413533834

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-[3-chloro-4-(4-phenylthiazol-2-yl)sulfanyl-anilino]-3-cyano-7-ethoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide

Formula:  C33H29ClN6O2S2

Similarity:  0.6363636363636364

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-[3-chloro-4-(imidazol-1-ylmethyl)anilino]-3-cyano-7-ethoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide

Formula:  C28H28ClN7O2

Similarity:  0.6363636363636364

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-[3-chloro-4-(3-pyridylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide

Formula:  C30H29ClN6O3

Similarity:  0.6323529411764706

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-[3-chloro-4-[(4-phenylthiazol-2-yl)methyl]anilino]-3-cyano-7-methoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide

Formula:  C33H29ClN6O2S

Similarity:  0.6267605633802817

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-[3-chloro-4-[(1-methylimidazol-2-yl)methoxy]anilino]-3-cyano-7-ethoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide

Formula:  C29H30ClN7O3

Similarity:  0.625

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-methoxy-6-quinolyl]-4-(diethylamino)but-2-enamide

Formula:  C25H25ClFN5O2

Similarity:  0.624

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |