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Approved Drugs
Name: Neratinib
Formula: C30H29ClN6O3
Similarity: 0.6482758620689655
Inhibitors
Name: (E)-4-(azetidin-1-yl)-N-[4-(4-benzyloxy-3-chloro-anilino)-3-cyano-7-ethoxy-6-quinolyl]but-2-enamide
Formula: C32H30ClN5O3
Similarity: 0.8984375
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(4-benzyloxy-3-chloro-anilino)-3-cyano-7-ethoxy-6-quinolyl]-4-pyrrolidin-1-yl-but-2-enamide
Formula: C33H32ClN5O3
Similarity: 0.8854961832061069
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(4-benzyloxy-3-chloro-anilino)-3-cyano-7-ethoxy-6-quinolyl]-4-(1-piperidyl)but-2-enamide
Formula: C34H34ClN5O3
Similarity: 0.8656716417910447
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(4-benzyloxy-3-chloro-anilino)-3-cyano-7-ethoxy-6-quinolyl]-4-morpholino-but-2-enamide
Formula: C33H32ClN5O4
Similarity: 0.8656716417910447
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(4-benzyloxy-3-chloro-anilino)-3-cyano-7-ethoxy-6-quinolyl]-4-(4-methylpiperazin-1-yl)but-2-enamide
Formula: C34H35ClN6O3
Similarity: 0.8529411764705882
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(4-benzyloxy-3-chloro-anilino)-3-cyano-7-ethoxy-6-quinolyl]-4-(4-hydroxy-1-piperidyl)but-2-enamide
Formula: C34H34ClN5O4
Similarity: 0.8529411764705882
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(4-benzyloxy-3-chloro-anilino)-3-cyano-7-ethoxy-6-quinolyl]-4-(4,4-dihydroxy-1-piperidyl)but-2-enamide
Formula: C34H34ClN5O5
Similarity: 0.8405797101449275
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(4-benzyloxy-3-chloro-anilino)-3-cyano-7-ethoxy-6-quinolyl]-4-[2-(methoxymethyl)pyrrolidin-1-yl]but-2-enamide
Formula: C35H36ClN5O4
Similarity: 0.7708333333333334
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(4-benzyloxy-3-chloro-anilino)-3-cyano-7-ethoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C31H30ClN5O3
Similarity: 0.7703703703703704
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(4-benzyloxy-3-chloro-anilino)-3-cyano-7-ethoxy-6-quinolyl]-4-(2,6-dimethyl-1-piperidyl)but-2-enamide
Formula: C36H38ClN5O3
Similarity: 0.7638888888888888
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(4-benzyloxy-3-chloro-anilino)-3-cyano-7-ethoxy-6-quinolyl]-4-(1,4,7-trioxa-10-azacyclododec-10-yl)but-2-enamide
Formula: C37H40ClN5O6
Similarity: 0.7631578947368421
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: methyl1-[(E)-4-[[4-(4-benzyloxy-3-chloro-anilino)-3-cyano-7-ethoxy-6-quinolyl]amino]-4-oxo-but-2-enyl]aziridine-2-carboxylate
Formula: C33H30ClN5O5
Similarity: 0.7552447552447552
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(4-benzyloxy-3-chloro-anilino)-3-cyano-7-ethoxy-6-quinolyl]-4-[2-hydroxyethyl(methyl)amino]but-2-enamide
Formula: C32H32ClN5O4
Similarity: 0.7375886524822695
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(4-benzyloxy-3-chloro-anilino)-3-cyano-7-ethoxy-6-quinolyl]-4-(1H-imidazol-4-yl)but-2-enamide
Formula: C32H27ClN6O3
Similarity: 0.7272727272727273
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(4-benzyloxy-3-chloro-anilino)-3-cyano-7-ethoxy-6-quinolyl]-4-[2-methoxyethyl(methyl)amino]but-2-enamide
Formula: C33H34ClN5O4
Similarity: 0.7222222222222222
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: N-[4-(4-benzyloxy-3-chloro-anilino)-3-cyano-7-ethoxy-6-quinolyl]-2-(morpholinomethyl)prop-2-enamide
Formula: C33H32ClN5O4
Similarity: 0.7172413793103448
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(4-benzyloxy-3-chloro-anilino)-3-cyano-7-ethoxy-6-quinolyl]-4-(diisopropylamino)but-2-enamide
Formula: C35H38ClN5O3
Similarity: 0.7172413793103448
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(4-benzyloxy-3-chloro-anilino)-3-cyano-7-ethoxy-6-quinolyl]-3-(1-methylimidazol-4-yl)prop-2-enamide
Formula: C32H27ClN6O3
Similarity: 0.7083333333333334
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-[3-chloro-4-(2-phenylethoxy)anilino]-3-cyano-7-ethoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C32H32ClN5O3
Similarity: 0.704225352112676
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |