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Approved Drugs
Name: Neratinib
Formula: C30H29ClN6O3
Similarity: 0.6122448979591837
Inhibitors
Name: (E)-N-[4-[3-chloro-4-(4-phenylthiazol-2-yl)sulfanyl-anilino]-3-cyano-7-ethoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C33H29ClN6O2S2
Similarity: 0.7785714285714286
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-[3-chloro-4-[(4-phenylthiazol-2-yl)methyl]anilino]-3-cyano-7-methoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C33H29ClN6O2S
Similarity: 0.7446808510638298
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-chloro-4-thiazol-2-ylsulfanyl-anilino)-3-cyano-7-methoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C26H23ClN6O2S2
Similarity: 0.7404580152671756
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-chloro-4-pyrimidin-2-ylsulfanyl-anilino)-3-cyano-7-methoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C27H24ClN7O2S
Similarity: 0.7111111111111111
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(4-benzyloxy-3-chloro-anilino)-3-cyano-7-methoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C30H28ClN5O3
Similarity: 0.708029197080292
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-[4-(benzylamino)-3-chloro-anilino]-3-cyano-7-methoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C30H29ClN6O2
Similarity: 0.708029197080292
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-[4-(anilinomethylamino)-3-chloro-anilino]-3-cyano-7-methoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C30H30ClN7O2
Similarity: 0.6928571428571428
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-[3-chloro-4-(1-methylimidazol-2-yl)sulfanyl-anilino]-3-cyano-7-methoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C27H26ClN7O2S
Similarity: 0.6911764705882353
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-[(1-benzylindazol-5-yl)amino]-3-cyano-7-methoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C31H29N7O2
Similarity: 0.676056338028169
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-chloro-4-phenoxy-anilino)-3-cyano-7-ethoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C30H28ClN5O3
Similarity: 0.6595744680851063
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-[3-chloro-4-(3-pyridylmethylamino)anilino]-3-cyano-7-methoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C29H28ClN7O2
Similarity: 0.647887323943662
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-[4-(benzylamino)-3-chloro-anilino]-3-cyano-7-ethoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C31H31ClN6O2
Similarity: 0.6458333333333334
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(4-benzyloxy-3-chloro-anilino)-3-cyano-7-ethoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C31H30ClN5O3
Similarity: 0.6458333333333334
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(4-benzyloxyanilino)-3-cyano-7-methoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C30H29N5O3
Similarity: 0.6453900709219859
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-methoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C23H21ClFN5O2
Similarity: 0.6434108527131783
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-[3-chloro-4-[(1R)-1-phenylethoxy]anilino]-3-cyano-7-ethoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C32H32ClN5O3
Similarity: 0.636986301369863
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-[4-[benzyl(methyl)amino]-3-chloro-anilino]-3-cyano-7-ethoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C32H33ClN6O2
Similarity: 0.636986301369863
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-[3-chloro-4-[(1S)-1-phenylethoxy]anilino]-3-cyano-7-ethoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C32H32ClN5O3
Similarity: 0.636986301369863
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-[3-chloro-4-[(2-methoxyphenyl)methoxy]anilino]-3-cyano-7-ethoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C32H32ClN5O4
Similarity: 0.6351351351351351
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |