Searching results
Approved Drugs
Name: Neratinib
Formula: C30H29ClN6O3
Similarity: 0.6363636363636364
Inhibitors
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-methoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C23H21ClFN5O2
Similarity: 0.7685185185185185
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-[3-chloro-4-(imidazol-1-ylmethyl)anilino]-3-cyano-7-ethoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C28H28ClN7O2
Similarity: 0.75
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-[3-chloro-4-(1-methylimidazol-2-yl)sulfanyl-anilino]-3-cyano-7-methoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C27H26ClN7O2S
Similarity: 0.7416666666666667
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-chloro-4-thiazol-2-ylsulfanyl-anilino)-3-cyano-7-methoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C26H23ClN6O2S2
Similarity: 0.725
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-chloro-4-pyrimidin-2-ylsulfanyl-anilino)-3-cyano-7-methoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C27H24ClN7O2S
Similarity: 0.7213114754098361
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-[3-chloro-4-(3-pyridylmethylamino)anilino]-3-cyano-7-methoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C29H28ClN7O2
Similarity: 0.717741935483871
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-bromoanilino)-3-cyano-7-methoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C23H22BrN5O2
Similarity: 0.7027027027027027
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-ethoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C24H23ClFN5O2
Similarity: 0.6869565217391305
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(4-benzyloxy-3-chloro-anilino)-3-cyano-7-methoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C30H28ClN5O3
Similarity: 0.6771653543307087
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-[4-(benzylamino)-3-chloro-anilino]-3-cyano-7-methoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C30H29ClN6O2
Similarity: 0.6771653543307087
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-[3-chloro-4-(4-pyridyloxy)anilino]-3-cyano-7-ethoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C29H27ClN6O3
Similarity: 0.6640625
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-[4-(anilinomethylamino)-3-chloro-anilino]-3-cyano-7-methoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C30H30ClN7O2
Similarity: 0.6615384615384615
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-methoxy-6-quinolyl]-4-(diethylamino)but-2-enamide
Formula: C25H25ClFN5O2
Similarity: 0.6554621848739496
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-[3-chloro-4-[(1-methylimidazol-2-yl)methoxy]anilino]-3-cyano-7-ethoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C29H30ClN7O3
Similarity: 0.6538461538461539
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-chloro-4-morpholino-anilino)-3-cyano-7-ethoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C28H31ClN6O3
Similarity: 0.6535433070866141
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-(trifluoromethoxy)-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C23H18ClF4N5O2
Similarity: 0.65
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-[3-chloro-4-(3-pyridylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C30H29ClN6O3
Similarity: 0.648854961832061
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C30H29ClN6O3
Similarity: 0.6363636363636364
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-methoxy-6-quinolyl]-4-(dimethylamino)pent-2-enamide
Formula: C24H23ClFN5O2
Similarity: 0.635593220338983
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |