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Approved Drugs

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Inhibitors

Name:  (E)-N'-[4-(3-chloro-4-fluoro-anilino)pyrido[3,4-d]pyrimidin-6-yl]-N-(3-morpholinopropyl)but-2-enediamide

Formula:  C24H25ClFN7O3

Similarity:  0.8070175438596491

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N'-[4-(3-bromoanilino)pyrido[3,4-d]pyrimidin-6-yl]-N-[3-(dimethylamino)propyl]but-2-enediamide

Formula:  C22H24BrN7O2

Similarity:  0.7232142857142857

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N'-[4-(3-bromoanilino)pyrido[3,4-d]pyrimidin-6-yl]-N-(3-imidazol-1-ylpropyl)but-2-enediamide

Formula:  C23H21BrN8O2

Similarity:  0.717948717948718

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N'-[4-(3-bromoanilino)pyrido[3,4-d]pyrimidin-6-yl]-N-[3-(diethylamino)propyl]but-2-enediamide

Formula:  C24H28BrN7O2

Similarity:  0.6864406779661016

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-(3-bromoanilino)pyrido[3,4-d]pyrimidin-6-yl]-N-(3-morpholinopropyl)prop-2-enamide

Formula:  C23H25BrN6O2

Similarity:  0.652542372881356

Relative Targets:   Epidermal growth factor receptor  |

Name:  ethyl(E)-4-[[4-(3-bromoanilino)pyrido[3,4-d]pyrimidin-6-yl]amino]-4-oxo-but-2-enoate

Formula:  C19H16BrN5O3

Similarity:  0.625

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-bromoanilino)quinazolin-6-yl]-4-morpholino-but-2-enamide

Formula:  C22H22BrN5O2

Similarity:  0.6101694915254238

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  N-[4-(3-bromoanilino)-7-(3-morpholinopropoxy)quinazolin-6-yl]prop-2-enamide

Formula:  C24H26BrN5O3

Similarity:  0.6097560975609756

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)pyrido[3,4-d]pyrimidin-6-yl]-4-morpholino-but-2-enamide

Formula:  C21H20ClFN6O2

Similarity:  0.6

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Receptor tyrosine-protein kinase erbB-4  |

Name:  (E)-N-[4-(3-bromoanilino)pyrido[3,4-d]pyrimidin-6-yl]but-2-enamide

Formula:  C17H14BrN5O

Similarity:  0.5981308411214953

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-bromoanilino)pyrido[3,4-d]pyrimidin-6-yl]-3-chloro-prop-2-enamide

Formula:  C16H11BrClN5O

Similarity:  0.5981308411214953

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-(3-bromoanilino)quinazolin-6-yl]-N-(3-morpholinopropyl)prop-2-enamide

Formula:  C24H26BrN5O2

Similarity:  0.5853658536585366

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N'-[4-(3-bromoanilino)quinazolin-6-yl]-N-[3-(dimethylamino)propyl]but-2-enediamide

Formula:  C23H25BrN6O2

Similarity:  0.5819672131147541

Relative Targets:   Epidermal growth factor receptor  |

Name:  (2E)-N-[4-(3-bromoanilino)pyrido[3,4-d]pyrimidin-6-yl]penta-2,4-dienamide

Formula:  C18H14BrN5O

Similarity:  0.5818181818181818

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N'-[4-(3-bromoanilino)pyrido[3,4-d]pyrimidin-6-yl]-N-[3-(dimethylamino)propyl]-N'-methyl-but-2-enediamide

Formula:  C23H26BrN7O2

Similarity:  0.5725806451612904

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-bromoanilino)quinazolin-6-yl]-3-morpholino-prop-2-enamide

Formula:  C21H20BrN5O2

Similarity:  0.5714285714285714

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  N-[4-(3-bromoanilino)pyrido[3,4-d]pyrimidin-6-yl]prop-2-enamide

Formula:  C16H12BrN5O

Similarity:  0.5700934579439252

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-(3-bromoanilino)quinazolin-6-yl]-2-(morpholinomethyl)prop-2-enamide

Formula:  C22H22BrN5O2

Similarity:  0.5619834710743802

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  N-[4-(3-bromoanilino)quinazolin-6-yl]-4-morpholino-but-2-ynamide

Formula:  C22H20BrN5O2

Similarity:  0.5447154471544715

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |