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Approved Drugs

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Inhibitors

Name:  N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-6-quinolyl]-2-(morpholinomethyl)prop-2-enamide

Formula:  C24H21ClFN5O2

Similarity:  0.7830188679245284

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-methoxy-6-quinolyl]-4-morpholino-but-2-enamide

Formula:  C25H23ClFN5O3

Similarity:  0.7727272727272727

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-6-quinolyl]-4-(dimethylamino)but-2-enamide

Formula:  C22H19ClFN5O

Similarity:  0.7047619047619048

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-bromoanilino)-3-cyano-7-methoxy-6-quinolyl]-4-morpholino-but-2-enamide

Formula:  C25H24BrN5O3

Similarity:  0.635593220338983

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-bromoanilino)-3-cyano-8-methoxy-6-quinolyl]-4-morpholino-but-2-enamide

Formula:  C25H24BrN5O3

Similarity:  0.635593220338983

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)pyrido[3,4-d]pyrimidin-6-yl]-4-morpholino-but-2-enamide

Formula:  C21H20ClFN6O2

Similarity:  0.6228070175438597

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Receptor tyrosine-protein kinase erbB-4  |

Name:  (E)-N-[4-(3-bromoanilino)-3-cyano-7-ethoxy-6-quinolyl]-4-morpholino-but-2-enamide

Formula:  C26H26BrN5O3

Similarity:  0.6198347107438017

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-methoxy-6-quinolyl]-4-morpholino-pent-2-enamide

Formula:  C26H25ClFN5O3

Similarity:  0.6147540983606558

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(4-benzyloxy-3-chloro-anilino)-3-cyano-7-ethoxy-6-quinolyl]-4-morpholino-but-2-enamide

Formula:  C33H32ClN5O4

Similarity:  0.5942028985507246

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-bromoanilino)quinazolin-6-yl]-4-morpholino-but-2-enamide

Formula:  C22H22BrN5O2

Similarity:  0.591304347826087

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-chloro-4-morpholino-anilino)-3-cyano-7-ethoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide

Formula:  C28H31ClN6O3

Similarity:  0.549618320610687

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-bromoanilino)-3-cyano-6-quinolyl]-4-(dimethylamino)but-2-enamide

Formula:  C22H20BrN5O

Similarity:  0.5391304347826087

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-bromoanilino)-3-cyano-6-quinolyl]but-2-enamide

Formula:  C20H15BrN4O

Similarity:  0.5363636363636364

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-methoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide

Formula:  C23H21ClFN5O2

Similarity:  0.5333333333333333

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-ethoxy-6-quinolyl]but-2-enamide

Formula:  C22H18ClFN4O2

Similarity:  0.5299145299145299

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(4-benzyloxy-3-chloro-anilino)-3-cyano-7-ethoxy-6-quinolyl]-4-(1,4,7-trioxa-10-azacyclododec-10-yl)but-2-enamide

Formula:  C37H40ClN5O6

Similarity:  0.5256410256410257

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-ethoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide

Formula:  C24H23ClFN5O2

Similarity:  0.5203252032520326

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-4-(azetidin-1-yl)-N-[4-(4-benzyloxy-3-chloro-anilino)-3-cyano-7-ethoxy-6-quinolyl]but-2-enamide

Formula:  C32H30ClN5O3

Similarity:  0.5106382978723404

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  N-[4-(3-bromoanilino)-3-cyano-6-quinolyl]prop-2-enamide

Formula:  C19H13BrN4O

Similarity:  0.509090909090909

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |