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Approved Drugs
Name: Dacomitinib
Formula: C24H25ClFN5O2
Similarity: 0.5271317829457365
Inhibitors
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-methoxy-6-quinolyl]-4-morpholino-but-2-enamide
Formula: C25H23ClFN5O3
Similarity: 0.8035714285714286
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-methoxy-6-quinolyl]-4-(dimethylamino)pent-2-enamide
Formula: C24H23ClFN5O2
Similarity: 0.7232142857142857
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-methoxy-6-quinolyl]-4-(diethylamino)pent-2-enamide
Formula: C26H27ClFN5O2
Similarity: 0.6864406779661016
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-methoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C23H21ClFN5O2
Similarity: 0.6754385964912281
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-ethoxy-6-quinolyl]but-2-enamide
Formula: C22H18ClFN4O2
Similarity: 0.6460176991150443
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-methoxy-6-quinolyl]-4-(diethylamino)but-2-enamide
Formula: C25H25ClFN5O2
Similarity: 0.6416666666666667
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-bromoanilino)-3-cyano-7-methoxy-6-quinolyl]-4-morpholino-but-2-enamide
Formula: C25H24BrN5O3
Similarity: 0.639344262295082
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-chloro-4-morpholino-anilino)-3-cyano-7-ethoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C28H31ClN6O3
Similarity: 0.627906976744186
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-6-quinolyl]-4-morpholino-but-2-enamide
Formula: C24H21ClFN5O2
Similarity: 0.6147540983606558
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-ethoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C24H23ClFN5O2
Similarity: 0.6033057851239669
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-(trifluoromethoxy)-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C23H18ClF4N5O2
Similarity: 0.584
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-bromoanilino)-3-cyano-7-ethoxy-6-quinolyl]-4-morpholino-but-2-enamide
Formula: C26H26BrN5O3
Similarity: 0.5736434108527132
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-6-quinolyl]-2-(morpholinomethyl)prop-2-enamide
Formula: C24H21ClFN5O2
Similarity: 0.5555555555555556
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-chloro-4-imidazol-1-yl-anilino)-3-cyano-7-methoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C26H24ClN7O2
Similarity: 0.5454545454545454
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(4-benzyloxy-3-chloro-anilino)-3-cyano-7-ethoxy-6-quinolyl]-4-morpholino-but-2-enamide
Formula: C33H32ClN5O4
Similarity: 0.54421768707483
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (Z)-N-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-2-fluoro-4-morpholin-4-ylbut-2-enamide
Formula: C23H22ClF2N5O3
Similarity: 0.5426356589147286
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-2-fluoro-4-morpholin-4-ylbut-2-enamide
Formula: C23H22ClF2N5O3
Similarity: 0.5426356589147286
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(3-morpholinopropoxy)quinazolin-6-yl]but-2-enamide
Formula: C25H27ClFN5O3
Similarity: 0.5378787878787878
Relative Targets: Epidermal growth factor receptor |
Name: N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-ethoxy-6-quinolyl]-2-[(dimethylamino)methyl]prop-2-enamide
Formula: C24H23ClFN5O2
Similarity: 0.5317460317460317
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |