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Approved Drugs
Name: Dacomitinib
Formula: C24H25ClFN5O2
Similarity: 0.5078125
Inhibitors
Name: (E)-N-[4-(3-bromoanilino)-3-cyano-7-ethoxy-6-quinolyl]-4-morpholino-but-2-enamide
Formula: C26H26BrN5O3
Similarity: 0.8952380952380953
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-bromoanilino)-3-cyano-8-methoxy-6-quinolyl]-4-morpholino-but-2-enamide
Formula: C25H24BrN5O3
Similarity: 0.8148148148148148
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-methoxy-6-quinolyl]-4-morpholino-but-2-enamide
Formula: C25H23ClFN5O3
Similarity: 0.8
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-bromoanilino)-3-cyano-7-methoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C23H22BrN5O2
Similarity: 0.7129629629629629
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: N-[4-(3-bromoanilino)-3-cyano-7-methoxy-6-quinolyl]prop-2-enamide
Formula: C20H15BrN4O2
Similarity: 0.6893203883495146
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-methoxy-6-quinolyl]-4-morpholino-pent-2-enamide
Formula: C26H25ClFN5O3
Similarity: 0.639344262295082
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-6-quinolyl]-4-morpholino-but-2-enamide
Formula: C24H21ClFN5O2
Similarity: 0.635593220338983
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-bromoanilino)-3-cyano-7-ethoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C24H24BrN5O2
Similarity: 0.6347826086956522
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(4-benzyloxy-3-chloro-anilino)-3-cyano-7-ethoxy-6-quinolyl]-4-morpholino-but-2-enamide
Formula: C33H32ClN5O4
Similarity: 0.6277372262773723
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: N-[4-(3-bromoanilino)-3-cyano-7-methoxy-6-quinolyl]but-2-ynamide
Formula: C21H15BrN4O2
Similarity: 0.6238532110091743
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: N-[4-(3-bromoanilino)-3-cyano-7-methoxy-6-quinolyl]-4-methoxy-but-2-ynamide
Formula: C22H17BrN4O3
Similarity: 0.6052631578947368
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-chloro-4-morpholino-anilino)-3-cyano-7-ethoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C28H31ClN6O3
Similarity: 0.5968992248062015
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: N-[4-(3-bromoanilino)-3-cyano-7-methoxy-6-quinolyl]-4-(dimethylamino)but-2-ynamide
Formula: C23H20BrN5O2
Similarity: 0.5948275862068966
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-bromoanilino)quinazolin-6-yl]-4-morpholino-but-2-enamide
Formula: C22H22BrN5O2
Similarity: 0.576271186440678
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-bromoanilino)-3-cyano-8-methoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C23H22BrN5O2
Similarity: 0.5677966101694916
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-methoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C23H21ClFN5O2
Similarity: 0.5583333333333333
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(4-benzyloxy-3-chloro-anilino)-3-cyano-7-ethoxy-6-quinolyl]-4-(1,4,7-trioxa-10-azacyclododec-10-yl)but-2-enamide
Formula: C37H40ClN5O6
Similarity: 0.5548387096774193
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: N-[4-(3-bromoanilino)-7-(3-morpholinopropoxy)quinazolin-6-yl]prop-2-enamide
Formula: C24H26BrN5O3
Similarity: 0.552
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-ethynylanilino)-7-methoxy-quinazolin-6-yl]-4-(1-piperidyl)but-2-enamide
Formula: C26H27N5O2
Similarity: 0.552
Relative Targets: Epidermal growth factor receptor |