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Approved Drugs

Name:  Dacomitinib

Formula:  C24H25ClFN5O2

Similarity:  0.5

Inhibitors

Name:  (E)-N-[4-(3-bromoanilino)quinazolin-6-yl]-4-(1-piperidyl)but-2-enamide

Formula:  C23H24BrN5O

Similarity:  0.7962962962962963

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-bromoanilino)quinazolin-6-yl]-4-morpholino-but-2-enamide

Formula:  C22H22BrN5O2

Similarity:  0.6869565217391305

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-bromoanilino)quinazolin-6-yl]-4-thiomorpholino-but-2-enamide

Formula:  C22H22BrN5OS

Similarity:  0.6869565217391305

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-bromoanilino)quinazolin-6-yl]-4-[(2R)-2-(methoxymethyl)pyrrolidin-1-yl]but-2-enamide

Formula:  C24H26BrN5O2

Similarity:  0.6311475409836066

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (Z)-N-[4-(3-bromoanilino)quinazolin-6-yl]-4-[(2S)-2-(methoxymethyl)pyrrolidin-1-yl]but-2-enamide

Formula:  C24H26BrN5O2

Similarity:  0.6311475409836066

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-bromoanilino)quinazolin-6-yl]-4-[(2S)-2-(methoxymethyl)pyrrolidin-1-yl]but-2-enamide

Formula:  C24H26BrN5O2

Similarity:  0.6311475409836066

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  N-[4-(3-bromoanilino)quinazolin-6-yl]-4-(1-piperidyl)but-2-ynamide

Formula:  C23H22BrN5O

Similarity:  0.6166666666666667

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (2R,3S)-N-[4-(3-bromoanilino)quinazolin-6-yl]-3-(1-piperidylmethyl)oxirane-2-carboxamide

Formula:  C23H24BrN5O2

Similarity:  0.6147540983606558

Relative Targets:   Proto-oncogene tyrosine-protein kinase Src  | Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-bromoanilino)quinazolin-6-yl]-3-morpholino-prop-2-enamide

Formula:  C21H20BrN5O2

Similarity:  0.5916666666666667

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-bromoanilino)quinazolin-6-yl]-4-methoxy-but-2-enamide

Formula:  C19H17BrN4O2

Similarity:  0.5877192982456141

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-bromoanilino)quinazolin-6-yl]-4-pyrazol-1-yl-but-2-enamide

Formula:  C21H17BrN6O

Similarity:  0.5785123966942148

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-bromoanilino)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C20H20BrN5O

Similarity:  0.5775862068965517

Relative Targets:   Proto-oncogene tyrosine-protein kinase Src  | Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-bromoanilino)quinazolin-6-yl]but-2-enamide

Formula:  C18H15BrN4O

Similarity:  0.5765765765765766

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (Z)-N-[4-(3-bromoanilino)quinazolin-6-yl]but-2-enamide

Formula:  C18H15BrN4O

Similarity:  0.5765765765765766

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-bromoanilino)quinazolin-6-yl]-3-(dimethylamino)prop-2-enamide

Formula:  C19H18BrN5O

Similarity:  0.5517241379310345

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-4-[[4-(3-bromoanilino)quinazolin-6-yl]amino]-4-oxo-but-2-enoicacid

Formula:  C18H13BrN4O3

Similarity:  0.5517241379310345

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-bromoanilino)quinazolin-6-yl]-4-oxo-pent-2-enamide

Formula:  C19H15BrN4O2

Similarity:  0.5517241379310345

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-(3-bromoanilino)quinazolin-6-yl]prop-2-enamide

Formula:  C17H13BrN4O

Similarity:  0.5495495495495496

Relative Targets:   Proto-oncogene tyrosine-protein kinase Src  | Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Proto-oncogene tyrosine-protein kinase Src  |

Name:  (E)-N-[4-(3-bromoanilino)quinazolin-6-yl]-4-[2-hydroxyethyl(methyl)amino]but-2-enamide

Formula:  C21H22BrN5O2

Similarity:  0.5491803278688525

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |