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Approved Drugs
Name: Afatinib
Formula: C24H25ClFN5O3
Similarity: 0.5
Inhibitors
Name: (E)-4-(dimethylamino)-N-[4-(3-iodoanilino)quinazolin-6-yl]but-2-enamide
Formula: C20H20IN5O
Similarity: 0.8554216867469879
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-bromoanilino)quinazolin-6-yl]-3-(dimethylamino)prop-2-enamide
Formula: C19H18BrN5O
Similarity: 0.8414634146341463
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-bromoanilino)quinazolin-6-yl]-4-[2-hydroxyethyl(methyl)amino]but-2-enamide
Formula: C21H22BrN5O2
Similarity: 0.8181818181818182
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-bromoanilino)quinazolin-6-yl]-4-(diethylamino)but-2-enamide
Formula: C22H24BrN5O
Similarity: 0.8181818181818182
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-bromoanilino)quinazolin-6-yl]-4-[2-methoxyethyl(methyl)amino]but-2-enamide
Formula: C22H24BrN5O2
Similarity: 0.8111111111111111
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-bromoanilino)quinazolin-6-yl]-4-methoxy-but-2-enamide
Formula: C19H17BrN4O2
Similarity: 0.8095238095238095
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-bromoanilino)quinazolin-6-yl]but-2-enamide
Formula: C18H15BrN4O
Similarity: 0.8024691358024691
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (Z)-N-[4-(3-bromoanilino)quinazolin-6-yl]but-2-enamide
Formula: C18H15BrN4O
Similarity: 0.8024691358024691
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-bromoanilino)quinazolin-6-yl]-4-(dipropylamino)but-2-enamide
Formula: C24H28BrN5O
Similarity: 0.7659574468085106
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-bromoanilino)quinazolin-6-yl]-4-oxo-pent-2-enamide
Formula: C19H15BrN4O2
Similarity: 0.7558139534883721
Relative Targets: Epidermal growth factor receptor |
Name: N-[4-(3-bromoanilino)quinazolin-6-yl]prop-2-enamide
Formula: C17H13BrN4O
Similarity: 0.7439024390243902
Relative Targets: Proto-oncogene tyrosine-protein kinase Src | Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Proto-oncogene tyrosine-protein kinase Src |
Name: (E)-4-[[4-(3-bromoanilino)quinazolin-6-yl]amino]-4-oxo-but-2-enoicacid
Formula: C18H13BrN4O3
Similarity: 0.735632183908046
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N'-[4-(3-bromoanilino)quinazolin-6-yl]-N-[3-(dimethylamino)propyl]but-2-enediamide
Formula: C23H25BrN6O2
Similarity: 0.7319587628865979
Relative Targets: Epidermal growth factor receptor |
Name: 3-(dimethylamino)propyl(E)-4-[[4-(3-bromoanilino)quinazolin-6-yl]amino]-4-oxo-but-2-enoate
Formula: C23H24BrN5O3
Similarity: 0.7319587628865979
Relative Targets: Epidermal growth factor receptor |
Name: N-[4-(3-bromoanilino)quinazolin-6-yl]-4-(dimethylamino)but-2-ynamide
Formula: C20H18BrN5O
Similarity: 0.7303370786516854
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-bromoanilino)-3-cyano-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C22H20BrN5O
Similarity: 0.7282608695652174
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: ethyl(E)-4-[[4-(3-bromoanilino)quinazolin-6-yl]amino]-4-oxo-but-2-enoate
Formula: C20H17BrN4O3
Similarity: 0.7252747252747253
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-bromoanilino)quinazolin-6-yl]-4,4,4-trifluoro-but-2-enamide
Formula: C18H12BrF3N4O
Similarity: 0.7191011235955056
Relative Targets: Epidermal growth factor receptor |
Name: N-[4-(3-bromoanilino)quinazolin-6-yl]buta-2,3-dienamide
Formula: C18H13BrN4O
Similarity: 0.7176470588235294
Relative Targets: Epidermal growth factor receptor |