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Approved Drugs
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Inhibitors
Name: N-[4-(3-chloro-4-fluoro-anilino)pyrido[3,4-d]pyrimidin-6-yl]prop-2-enamide
Formula: C16H11ClFN5O
Similarity: 0.8378378378378378
Relative Targets: Epidermal growth factor receptor |
Name: N-[4-(3-bromoanilino)pyrido[3,4-d]pyrimidin-6-yl]prop-2-enamide
Formula: C16H12BrN5O
Similarity: 0.7631578947368421
Relative Targets: Epidermal growth factor receptor |
Name: N-[4-(3-bromo-4-fluoro-anilino)quinazolin-6-yl]prop-2-enamide
Formula: C17H12BrFN4O
Similarity: 0.7435897435897436
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: N-[4-(3-bromo-4-fluoro-anilino)pyrido[3,2-d]pyrimidin-6-yl]prop-2-enamide
Formula: C16H11BrFN5O
Similarity: 0.7215189873417721
Relative Targets: Epidermal growth factor receptor |
Name: N-[4-(3-methylanilino)pyrido[3,4-d]pyrimidin-6-yl]prop-2-enamide
Formula: C17H15N5O
Similarity: 0.717948717948718
Relative Targets: Epidermal growth factor receptor |
Name: N-[4-(3-bromoanilino)pyrido[4,3-d]pyrimidin-7-yl]prop-2-enamide
Formula: C16H12BrN5O
Similarity: 0.675
Relative Targets: Epidermal growth factor receptor |
Name: (2E)-N-[4-(3-bromoanilino)pyrido[3,4-d]pyrimidin-6-yl]penta-2,4-dienamide
Formula: C18H14BrN5O
Similarity: 0.6470588235294118
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)pyrido[3,4-d]pyrimidin-6-yl]-4-(dimethylamino)but-2-enamide
Formula: C19H18ClFN6O
Similarity: 0.6333333333333333
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-(3-bromoanilino)pyrido[3,4-d]pyrimidin-6-yl]but-2-enamide
Formula: C17H14BrN5O
Similarity: 0.6309523809523809
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-bromoanilino)pyrido[3,4-d]pyrimidin-6-yl]-3-chloro-prop-2-enamide
Formula: C16H11BrClN5O
Similarity: 0.6309523809523809
Relative Targets: Epidermal growth factor receptor |
Name: N-[4-(3-chloro-4-fluoro-anilino)quinazolin-6-yl]prop-2-enamide
Formula: C17H12ClFN4O
Similarity: 0.6190476190476191
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: N-[4-(3-chloro-4-fluoro-anilino)pyrido[3,2-d]pyrimidin-6-yl]prop-2-enamide
Formula: C16H11ClFN5O
Similarity: 0.6
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: N-[4-(3-bromoanilino)pyrido[3,4-d]pyrimidin-6-yl]-2-methyl-prop-2-enamide
Formula: C17H14BrN5O
Similarity: 0.6
Relative Targets: Epidermal growth factor receptor |
Name: N-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-quinazolin-6-yl]prop-2-enamide
Formula: C18H14ClFN4O2
Similarity: 0.5842696629213483
Relative Targets: Epidermal growth factor receptor |
Name: N-[4-(3-bromoanilino)quinazolin-6-yl]prop-2-enamide
Formula: C17H13BrN4O
Similarity: 0.5764705882352941
Relative Targets: Proto-oncogene tyrosine-protein kinase Src | Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Proto-oncogene tyrosine-protein kinase Src |
Name: N-[4-[3-bromo-4-[(dimethylamino)methyl]anilino]quinazolin-6-yl]prop-2-enamide
Formula: C20H20BrN5O
Similarity: 0.5652173913043478
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)pyrido[3,4-d]pyrimidin-6-yl]-4-(1-piperidyl)but-2-enamide
Formula: C22H22ClFN6O
Similarity: 0.5643564356435643
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)pyrido[3,4-d]pyrimidin-6-yl]-4-morpholino-but-2-enamide
Formula: C21H20ClFN6O2
Similarity: 0.5643564356435643
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: N-[4-(3-bromoanilino)quinazolin-7-yl]prop-2-enamide
Formula: C17H13BrN4O
Similarity: 0.5581395348837209
Relative Targets: Epidermal growth factor receptor |