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Approved Drugs

Name:  Neratinib

Formula:  C30H29ClN6O3

Similarity:  0.5193798449612403

Inhibitors

Name:  (E)-N-[4-(3-bromoanilino)-3-cyano-6-quinolyl]but-2-enamide

Formula:  C20H15BrN4O

Similarity:  0.813953488372093

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-6-quinolyl]-4-(dimethylamino)but-2-enamide

Formula:  C22H19ClFN5O

Similarity:  0.7659574468085106

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  N-[4-(3-bromoanilino)-3-cyano-6-quinolyl]prop-2-enamide

Formula:  C19H13BrN4O

Similarity:  0.7586206896551724

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-bromoanilino)-3-cyano-7-methoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide

Formula:  C23H22BrN5O2

Similarity:  0.7422680412371134

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-bromoanilino)-3-cyano-8-methoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide

Formula:  C23H22BrN5O2

Similarity:  0.7422680412371134

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-bromoanilino)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C20H20BrN5O

Similarity:  0.7282608695652174

Relative Targets:   Proto-oncogene tyrosine-protein kinase Src  | Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-bromoanilino)-3-cyano-7-ethoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide

Formula:  C24H24BrN5O2

Similarity:  0.72

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  N-[4-(3-bromoanilino)-3-cyano-6-quinolyl]but-2-ynamide

Formula:  C20H13BrN4O

Similarity:  0.6956521739130435

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  N-[4-(3-bromoanilino)-3-cyano-6-quinolyl]-4-methoxy-but-2-ynamide

Formula:  C21H15BrN4O2

Similarity:  0.6701030927835051

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  N-[4-(3-bromoanilino)-3-cyano-6-quinolyl]-3-(methoxymethoxy)prop-2-ynamide

Formula:  C21H15BrN4O3

Similarity:  0.65

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  N-[4-(3-bromoanilino)-3-cyano-6-quinolyl]-4-(diisopropylamino)but-2-ynamide

Formula:  C26H26BrN5O

Similarity:  0.6261682242990654

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-4-(dimethylamino)-N-[4-(3-iodoanilino)quinazolin-6-yl]but-2-enamide

Formula:  C20H20IN5O

Similarity:  0.6224489795918368

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-(3-bromoanilino)-3-cyano-6-quinolyl]-4-(dipropylamino)but-2-ynamide

Formula:  C26H26BrN5O

Similarity:  0.6146788990825688

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  N-[4-(3-bromoanilino)-3-cyano-6-quinolyl]-4-(2-methoxyethoxy)but-2-ynamide

Formula:  C23H19BrN4O3

Similarity:  0.6132075471698113

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-bromoanilino)quinazolin-6-yl]-3-(dimethylamino)prop-2-enamide

Formula:  C19H18BrN5O

Similarity:  0.6082474226804123

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-bromoanilino)quinazolin-6-yl]-4-[2-hydroxyethyl(methyl)amino]but-2-enamide

Formula:  C21H22BrN5O2

Similarity:  0.6019417475728155

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-bromoanilino)quinazolin-6-yl]-4-(diethylamino)but-2-enamide

Formula:  C22H24BrN5O

Similarity:  0.6019417475728155

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-bromoanilino)quinazolin-6-yl]-4-[2-methoxyethyl(methyl)amino]but-2-enamide

Formula:  C22H24BrN5O2

Similarity:  0.6

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-bromoanilino)quinazolin-6-yl]-4-methoxy-but-2-enamide

Formula:  C19H17BrN4O2

Similarity:  0.5858585858585859

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |