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Inhibitors

Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-[3-(4-methylpiperazin-1-yl)propoxy]pyrido[3,2-d]pyrimidin-6-yl]prop-2-enamide

Formula:  C24H27ClFN7O2

Similarity:  0.8165137614678899

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-(4-morpholinobutyl)pyrido[3,2-d]pyrimidin-6-yl]prop-2-enamide

Formula:  C24H26ClFN6O2

Similarity:  0.8148148148148148

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-(3-morpholinopropoxy)pyrido[3,2-d]pyrimidin-6-yl]-N-methyl-prop-2-enamide

Formula:  C24H26ClFN6O3

Similarity:  0.8

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  Canertinib

Formula:  C24H25ClFN5O3

Similarity:  0.7981651376146789

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Dipeptidyl peptidase 1  | Receptor tyrosine-protein kinase erbB-4  |

Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-(3-morpholinopropoxy)quinazolin-6-yl]prop-2-enamide;dihydrochloride

Formula:  C24H27Cl3FN5O3

Similarity:  0.7837837837837838

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Receptor tyrosine-protein kinase erbB-4  |

Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-[(E)-4-morpholinobut-1-enyl]pyrido[3,2-d]pyrimidin-6-yl]prop-2-enamide

Formula:  C24H24ClFN6O2

Similarity:  0.7657657657657657

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  N-[4-(3-bromo-4-fluoro-anilino)-7-(3-morpholinopropoxy)quinazolin-6-yl]prop-2-enamide

Formula:  C24H25BrFN5O3

Similarity:  0.7043478260869566

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(3-morpholinopropoxy)quinazolin-6-yl]but-2-enamide

Formula:  C25H27ClFN5O3

Similarity:  0.7008547008547008

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)pyrido[3,2-d]pyrimidin-6-yl]prop-2-enamide

Formula:  C19H17ClFN5O3

Similarity:  0.6981132075471698

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-(3-morpholinopropoxy)quinazolin-6-yl]-2-methyl-prop-2-enamide

Formula:  C25H27ClFN5O3

Similarity:  0.6923076923076923

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-pyrido[3,2-d]pyrimidin-6-yl]prop-2-enamide

Formula:  C17H13ClFN5O2

Similarity:  0.6601941747572816

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-(3-morpholinopropoxy)quinazolin-6-yl]cyclopentene-1-carboxamide

Formula:  C27H29ClFN5O3

Similarity:  0.6349206349206349

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-(3-methylanilino)-7-(3-morpholinopropoxy)quinazolin-6-yl]prop-2-enamide

Formula:  C25H29N5O3

Similarity:  0.6302521008403361

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-(3-bromoanilino)-7-(3-morpholinopropoxy)quinazolin-6-yl]prop-2-enamide

Formula:  C24H26BrN5O3

Similarity:  0.6302521008403361

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N'-[4-(3-chloro-4-fluoro-anilino)pyrido[3,4-d]pyrimidin-6-yl]-N-(3-morpholinopropyl)but-2-enediamide

Formula:  C24H25ClFN7O3

Similarity:  0.578125

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)pyrido[3,4-d]pyrimidin-6-yl]-4-morpholino-but-2-enamide

Formula:  C21H20ClFN6O2

Similarity:  0.5666666666666667

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Receptor tyrosine-protein kinase erbB-4  |

Name:  (Z)-N-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-2-fluoro-4-morpholin-4-ylbut-2-enamide

Formula:  C23H22ClF2N5O3

Similarity:  0.56

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-2-fluoro-4-morpholin-4-ylbut-2-enamide

Formula:  C23H22ClF2N5O3

Similarity:  0.56

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-(3-chloro-4-fluoro-anilino)pyrido[3,2-d]pyrimidin-6-yl]prop-2-enamide

Formula:  C16H11ClFN5O

Similarity:  0.5370370370370371

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |