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Approved Drugs
Inhibitors
Name:  Canertinib
Formula:  C24H25ClFN5O3
Similarity:  0.8846153846153846
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Dipeptidyl peptidase 1  | Receptor tyrosine-protein kinase erbB-4  |
Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-(3-morpholinopropoxy)quinazolin-6-yl]prop-2-enamide;dihydrochloride
Formula:  C24H27Cl3FN5O3
Similarity:  0.8679245283018868
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Receptor tyrosine-protein kinase erbB-4  |
Name:  N-[4-(3-bromoanilino)-7-(3-morpholinopropoxy)quinazolin-6-yl]prop-2-enamide
Formula:  C24H26BrN5O3
Similarity:  0.8301886792452831
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  N-[4-(3-methylanilino)-7-(3-morpholinopropoxy)quinazolin-6-yl]prop-2-enamide
Formula:  C25H29N5O3
Similarity:  0.7962962962962963
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(3-morpholinopropoxy)quinazolin-6-yl]but-2-enamide
Formula:  C25H27ClFN5O3
Similarity:  0.7767857142857143
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-(3-morpholinopropoxy)quinazolin-6-yl]-2-methyl-prop-2-enamide
Formula:  C25H27ClFN5O3
Similarity:  0.7522123893805309
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-(3-morpholinopropoxy)pyrido[3,2-d]pyrimidin-6-yl]prop-2-enamide
Formula:  C23H24ClFN6O3
Similarity:  0.7043478260869566
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-(3-morpholinopropoxy)quinazolin-6-yl]cyclopentene-1-carboxamide
Formula:  C27H29ClFN5O3
Similarity:  0.6885245901639344
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[4-(3-bromoanilino)-7-[3-(4-methylpiperazin-1-yl)propoxy]quinazolin-6-yl]prop-2-enamide
Formula:  C25H29BrN6O2
Similarity:  0.6752136752136753
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[4-(3-methylanilino)-7-[3-(4-methylpiperazin-1-yl)propoxy]quinazolin-6-yl]prop-2-enamide
Formula:  C26H32N6O2
Similarity:  0.6470588235294118
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-(3-morpholinopropoxy)pyrido[3,2-d]pyrimidin-6-yl]-N-methyl-prop-2-enamide
Formula:  C24H26ClFN6O3
Similarity:  0.6229508196721312
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  (Z)-N-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-2-fluoro-4-morpholin-4-ylbut-2-enamide
Formula:  C23H22ClF2N5O3
Similarity:  0.5983606557377049
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-2-fluoro-4-morpholin-4-ylbut-2-enamide
Formula:  C23H22ClF2N5O3
Similarity:  0.5983606557377049
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-(4-morpholinobutyl)pyrido[3,2-d]pyrimidin-6-yl]prop-2-enamide
Formula:  C24H26ClFN6O2
Similarity:  0.5934959349593496
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  N-[4-(3-cyano-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]prop-2-enamide
Formula:  C21H18FN5O3
Similarity:  0.591304347826087
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide
Formula:  C21H18ClFN4O3
Similarity:  0.5862068965517241
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[4-(3-Chloro-4-fluoroanilino)-7-prop-2-ynoxyquinazolin-6-yl]prop-2-enamide
Formula:  C20H14ClFN4O2
Similarity:  0.5803571428571429
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[4-(3-bromoanilino)-7-(3-imidazol-1-ylpropoxy)quinazolin-6-yl]prop-2-enamide
Formula:  C23H21BrN6O2
Similarity:  0.5785123966942148
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-[2-(4-hydroxybutoxy)ethoxy]quinazolin-6-yl]prop-2-enamide
Formula:  C23H24ClFN4O4
Similarity:  0.5737704918032787
Relative Targets:   Epidermal growth factor receptor  |