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Approved Drugs
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Inhibitors
Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-(3-morpholinopropoxy)pyrido[3,2-d]pyrimidin-6-yl]prop-2-enamide
Formula:  C23H24ClFN6O3
Similarity:  0.8
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  Canertinib
Formula:  C24H25ClFN5O3
Similarity:  0.7068965517241379
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Dipeptidyl peptidase 1  | Receptor tyrosine-protein kinase erbB-4  |
Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-(3-morpholinopropoxy)quinazolin-6-yl]prop-2-enamide;dihydrochloride
Formula:  C24H27Cl3FN5O3
Similarity:  0.6949152542372882
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Receptor tyrosine-protein kinase erbB-4  |
Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-(4-morpholinobutyl)pyrido[3,2-d]pyrimidin-6-yl]prop-2-enamide
Formula:  C24H26ClFN6O2
Similarity:  0.6779661016949152
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-[3-(4-methylpiperazin-1-yl)propoxy]pyrido[3,2-d]pyrimidin-6-yl]prop-2-enamide
Formula:  C24H27ClFN7O2
Similarity:  0.6666666666666666
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-(3-morpholinopropoxy)quinazolin-6-yl]-2-methyl-prop-2-enamide
Formula:  C25H27ClFN5O3
Similarity:  0.6666666666666666
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(3-morpholinopropoxy)quinazolin-6-yl]but-2-enamide
Formula:  C25H27ClFN5O3
Similarity:  0.6611570247933884
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-[(E)-4-morpholinobut-1-enyl]pyrido[3,2-d]pyrimidin-6-yl]prop-2-enamide
Formula:  C24H24ClFN6O2
Similarity:  0.6363636363636364
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  N-[4-(3-bromo-4-fluoro-anilino)-7-(3-morpholinopropoxy)quinazolin-6-yl]prop-2-enamide
Formula:  C24H25BrFN5O3
Similarity:  0.6229508196721312
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-(3-morpholinopropoxy)quinazolin-6-yl]cyclopentene-1-carboxamide
Formula:  C27H29ClFN5O3
Similarity:  0.6
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[4-(3-methylanilino)-7-(3-morpholinopropoxy)quinazolin-6-yl]prop-2-enamide
Formula:  C25H29N5O3
Similarity:  0.568
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[4-(3-bromoanilino)-7-(3-morpholinopropoxy)quinazolin-6-yl]prop-2-enamide
Formula:  C24H26BrN5O3
Similarity:  0.5555555555555556
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)pyrido[3,2-d]pyrimidin-6-yl]prop-2-enamide
Formula:  C19H17ClFN5O3
Similarity:  0.5555555555555556
Relative Targets:   Epidermal growth factor receptor  |
Name:  (Z)-N-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-2-fluoro-4-morpholin-4-ylbut-2-enamide
Formula:  C23H22ClF2N5O3
Similarity:  0.5390625
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-2-fluoro-4-morpholin-4-ylbut-2-enamide
Formula:  C23H22ClF2N5O3
Similarity:  0.5390625
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N'-[4-(3-chloro-4-fluoro-anilino)pyrido[3,4-d]pyrimidin-6-yl]-N-(3-morpholinopropyl)but-2-enediamide
Formula:  C24H25ClFN7O3
Similarity:  0.5338345864661654
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-pyrido[3,2-d]pyrimidin-6-yl]prop-2-enamide
Formula:  C17H13ClFN5O2
Similarity:  0.5309734513274337
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)pyrido[3,4-d]pyrimidin-6-yl]-4-morpholino-but-2-enamide
Formula:  C21H20ClFN6O2
Similarity:  0.52
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Receptor tyrosine-protein kinase erbB-4  |
Name:  N-[4-(3-bromoanilino)pyrido[3,4-d]pyrimidin-6-yl]-N-(3-morpholinopropyl)prop-2-enamide
Formula:  C23H25BrN6O2
Similarity:  0.5078125
Relative Targets:   Epidermal growth factor receptor  |