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Name:  Dacomitinib

Formula:  C₂₄H₂₅ClFN₅O₂

Similarity:  0.5135135135135135

Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)pyrido[3,2-d]pyrimidin-6-yl]prop-2-enamide

Formula:  C₁₉H₁₇ClFN₅O₃

Similarity:  0.8235294117647058

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-quinazolin-6-yl]prop-2-enamide

Formula:  C₁₈H₁₄ClFN₄O₂

Similarity:  0.7380952380952381

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-(3-chloro-4-fluoro-anilino)pyrido[3,2-d]pyrimidin-6-yl]prop-2-enamide

Formula:  C₁₆H₁₁ClFN₅O

Similarity:  0.6987951807228916

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-[3-(4-methylpiperazin-1-yl)propoxy]pyrido[3,2-d]pyrimidin-6-yl]prop-2-enamide

Formula:  C₂₄H₂₇ClFN₇O₂

Similarity:  0.6634615384615384

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-(3-morpholinopropoxy)pyrido[3,2-d]pyrimidin-6-yl]prop-2-enamide

Formula:  C₂₃H₂₄ClFN₆O₃

Similarity:  0.6601941747572816

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  N-[4-(3-chloro-4-fluoro-anilino)pyrido[3,4-d]pyrimidin-6-yl]prop-2-enamide

Formula:  C₁₆H₁₁ClFN₅O

Similarity:  0.6395348837209303

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-(3-chloro-4-fluoro-anilino)quinazolin-6-yl]prop-2-enamide

Formula:  C₁₇H₁₂ClFN₄O

Similarity:  0.6206896551724138

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  N-[4-(3-Chloro-4-fluoroanilino)-7-prop-2-ynoxyquinazolin-6-yl]prop-2-enamide

Formula:  C₂₀H₁₄ClFN₄O₂

Similarity:  0.6170212765957447

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-(4-morpholinobutyl)pyrido[3,2-d]pyrimidin-6-yl]prop-2-enamide

Formula:  C₂₄H₂₆ClFN₆O₂

Similarity:  0.5981308411214953

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-[(E)-4-morpholinobut-1-enyl]pyrido[3,2-d]pyrimidin-6-yl]prop-2-enamide

Formula:  C₂₄H₂₄ClFN₆O₂

Similarity:  0.5981308411214953

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  N-[4-(3-bromo-4-fluoro-anilino)pyrido[3,2-d]pyrimidin-6-yl]prop-2-enamide

Formula:  C₁₆H₁₁BrFN₅O

Similarity:  0.5842696629213483

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide

Formula:  C₂₁H₁₈ClFN₄O₃

Similarity:  0.5742574257425742

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-quinazolin-6-yl]-4-(cyclopropylamino)but-2-enamide

Formula:  C₂₂H₂₁ClFN₅O₂

Similarity:  0.5480769230769231

Relative Targets:   Epidermal growth factor receptor  |

Name:  (Z)-N-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide

Formula:  C₂₁H₂₀ClF₂N₅O₂

Similarity:  0.5436893203883495

Relative Targets:   Tyrosine-protein kinase JAK2  | Epidermal growth factor receptor  | Hepatocyte growth factor receptor  | Platelet-derived growth factor receptor alpha  | Fibroblast growth factor receptor 2  | RAC-beta serine/threonine-protein kinase  | Potassium voltage-gated channel subfamily H member 2  | Receptor tyrosine-protein kinase erbB-4  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-quinazolin-6-yl]-4-[cyclopropyl(methyl)amino]but-2-enamide

Formula:  C₂₃H₂₃ClFN₅O₂

Similarity:  0.5377358490566038

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[[2-[4-amino-6-(3-chloro-4-fluoro-anilino)pyrimidin-5-yl]oxazol-4-yl]methyl]prop-2-enamide

Formula:  C₁₇H₁₄ClFN₆O₂

Similarity:  0.5360824742268041

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  N-[4-(3-bromo-4-fluoro-anilino)pyrido[3,4-d]pyrimidin-6-yl]prop-2-enamide

Formula:  C₁₆H₁₁BrFN₅O

Similarity:  0.532608695652174

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-[2-(4-hydroxybutoxy)ethoxy]quinazolin-6-yl]prop-2-enamide

Formula:  C₂₃H₂₄ClFN₄O₄

Similarity:  0.5321100917431193

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-(3-morpholinopropoxy)pyrido[3,2-d]pyrimidin-6-yl]-N-methyl-prop-2-enamide

Formula:  C₂₄H₂₆ClFN₆O₃

Similarity:  0.5309734513274337

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |